Accepted Manuscript Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4- triazoles as potential combretastatin analogues Muhamad Mustafa, Dalia Abdelhamid, ElShimaa M.N. Abdelhafez, Mahmoud A.A. Ibrahim, Amira M. Gamal-Eldeen, Omar M. Aly PII: S0223-5234(17)30778-X DOI: 10.1016/j.ejmech.2017.09.063 Reference: EJMECH 9778 To appear in: European Journal of Medicinal Chemistry Received Date: 13 January 2017 Revised Date: 13 March 2017 Accepted Date: 27 September 2017 Please cite this article as: M. Mustafa, D. Abdelhamid, E.M.N. Abdelhafez, M.A.A. Ibrahim, A.M. Gamal- Eldeen, O.M. Aly, Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4- triazoles as potential combretastatin analogues, European Journal of Medicinal Chemistry (2017), doi: 10.1016/j.ejmech.2017.09.063. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.