Journal of Pharmaceutical Negative Results ¦ Volume 13 ¦ Issue 3 ¦ 2022 1060 Case Report on Brain Stem Glioma Urvashi Kapgate 1 , Bibin Kurian 2 , Aniket Pathade 3 1 B. BSc. nursing, Smt. Radhikabai Meghe Memorial College of Nursing Sawangi (Meghe), Wardha, Datta Meghe Institute of Medical Sciences (Deemed to be University) Maharashtra, India. 2 Associate Professor, Department of Child Health Nursing, Smt. Radhikabai Meghe Memorial College of Nursing Sawangi (Meghe), Wardha, Datta Meghe Institute of Medical Sciences (Deemed to be University) Maharashtra, India. 3 Research Scientist, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha, Maharashtra. Brain stem glioma is one of the diseases of CNS. It is brain and spinal cord tumor. It is a type of tumor caused when healthy cells in the brain stem change and increase abnormally and forms a mass that mass called as tumor. This tumor may be malignant. It grows abnormally and spread other parts of body. Glioma is a tumor, it grows from glial cell is supportive cell in the brain. A 13 year old male patient presented in neurology ward with the chief complaint of difficulty chewing and swallowing food, drooping of the face on left side, difficulty while talking, weakness in the left arms and legs, unable to walk along with Headache and Vomiting. After examination and specific investigation following blood test, cytology and MRI scan, the patient was diagnosed as brain stem glioma. Initial management was done by Physician by antibiotic, intravenous fluid, some vitamin and nutritional supplement and diuretics to remove fluid into body. Following the appropriate treatment patient’s condition improved day by day. Keywords: brain stem glioma, CNS, malignant, glial cell, pons. INTRODUCTION Brain stem glioma is one of most difficult pediatric cancer to treat. To diagnosed the brain stem glioma doctor advice to CT Scan, MRI and sophisticated neurophysiology monitoring techniques and advice to do surgical treatment of this disease condition.(1) Brain stem glioma is generally occurs in childhood. This disease formed in male and female in same proportion.(2) Brain stem glioma is a heterogeneous group of tumors. Brain stem glioma is difficult to diagnose and challenging to treat. Most of the brain stem cancer formed in the pons and developed in the part of the brain stem and they complicated to do surgery.(3) Therefore more than 60% of children are treated as the part of clinical practice. A clinical practice is research study that helps finding the best treatment. Clinical trials given a new drug, combination of existing treatments or recent dose of current therapies.(4) After giving clinical current therapies. After giving clinical practice medication observe the children and do close monitoring to see adverse effect.(5) Developed imaging and surgery, imaging techniques are developed that help the surgeon to located particular point of brain. Developed radiation therapy, Radiation therapy is given to the particular point of tumor not on healthy cell of the brain to stop the tumor growth and slow the growth of tumor. (6) In children, 10–20percent of all cancers of the nervous system are gliomas of the brain stem. Individuals who are under the age of 10 are more likely to have them. Glial cells inside the brain stem give rise to brain stem gliomas. Glial cells are the cells that make up the supporting tissues.(7) A brain stem glioma's behaviour, diagnosis, and growth pattern depend on where it develops (midbrain, pons, medulla), whether it does so (diffuse or confined, inherent or exophytic), and what type of glioma it really is (low grade or high grade). Access this article online Quick Response Code: Website: www.pnrjournal.com DOI: 10.47750/pnr.2022.13.03.170 Address for correspondence: Urvashi Kapgate Smt. Radhikabai Meghe Memorial College of Nursing. Datta Meghe Institute of Sciences (Deemed to be University) Maharashtra, India. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‑NonCommercial‑ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non‑commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. For reprints contact: pnrjournal@gmail.com How to cite this article: Urvashi Kapgate, Bibin Kurian, Aniket Pathade, Case Report on Brain Stem Glioma, J PHARM NEGATIVE RESULTS 2022;13: 1060- 1063.