Journal of Multidisciplinary Sciences www.multidisciplines.com J. Multidiscip. Sci. 2022, 4(2), 17-27. https://doi.org/10.33888/jms.2022.423 www.multidisciplines.com Advances in plant-based green synthesis of nanoparticles Anamika Roy 1 , Md. Iqbal Hossain 2 , and Pantu Kumar Roy 3 * 1 Department of Chemistry, Khulna University, Khulna 9208, Bangladesh. 2 Deptartment of Food and Nutrition, Chung-Ang University, Anseong 4726, Republic of Korea. 3 Institute of Marine Industry, Department of Seafood Science and Technology, Gyeongsang National University, Tongyeong 53064, Republic of Korea. *Corresponding authors' email address: vetpantu88@gmail.com (P.K.R.) Received: 15 October 2022; Accepted: 02 December 2022; Published online: 10 December 2022 Abstract. Important routes for the synthesis of nanoparticles include physical and chemical processes, which are typically costly and potentially dangerous to the environment. The assessment of eco-friendly chemistry or biological strategies for producing nanoparticles from plant extracts has attracted the interest of a large number of scientists in recent years. Before establishing a generally accepted method, researchers must investigate the plant-assisted synthesis of nanoparticles and their effects. It is gaining popularity because of its ability to facilitate the creation of alternative, safer, less toxic, sustainable, and environmentally friendly methods. The synthesis of novel nanoparticles with the necessary properties is mandatory for the development of cosmetics, biomedicine, biosensors, nano-biotechnology, and other applications involving antibacterial, catalytic, electronic, electrochemical, and sensing processes. Environmental and biological fields have numerous possible uses for the green synthesis of nanoparticles. It attempts specifically to decrease the use of harmful chemicals. Typically, employing biological resources, such as plants, is harmless. Also found in plants are reducing and capping agents. Here, we discuss the advancement of green synthesis of nanoparticles, the most current applications, and future perspectives. Keywords: Biogenic nanoparticles, biomedical applications, green chemistry, metal nanoparticles, and nanoparticle applications Cite this as: Roy, A., Hossain, M.I. & Roy, P.K. (2022). Advances in plant-based green synthesis of nanoparticles. J. Multidiscip. Sci. 4(2), 17-27. 1. Introduction Nanotechnology involves the separation, consolidation, and deformation of materials at the atomic or molecular level (Abdelbaky et al., 2022). In his words, it is the field of science concerned with manipulating matter at the atomic or molecular level. In the twenty-first century, nanotechnology became a scientific breakthrough. It is an interdisciplinary field that encompasses the invention, manipulation, and application of sub-100 nm-scale materials. It has focused on the molecular level and penetrated the enormous arena of applications (Mansoori, 2005; Afessa et al., 2022). Innovative practical and basic frontiers in a new sector of research, including materials science and engineering, have been unlocked by nanotechnology's exponential expansion (Dvir et al., 2011). Nanoscale structures (nanoparticles) play a crucial role in numerous significant technologies, including biomedical science, drug-gene delivery, electronics, mechanics, optics, the catalysis industry, the chemical industry, energy science, nonlinear optical devices, optoelectronic devices, photoelectrochemical systems, and space industry applications (Singh et al., 2020). Nanoparticles are extremely small in size (in nm), which results in both chemical and physical changes compared to most particles with a similar chemical makeup (Ray, 2010; Bakand et al., 2012). Numerous academics have shown a great deal of interest in the unique characteristics of nanoparticles and discovered their remarkable uses in a variety of areas; however, some have demonstrated nanoscale toxicity. To combat the issue of toxicity, green chemistry and nanotechnology combine to produce nature-friendly nanoparticles using microorganisms, plants, and other natural sources (Lateef et al., 2016). Numerous synthetic routes for nanoparticle production have been explored by scientists, revealing a significant benefit to nature and the environment through the use of "green chemistry" techniques, including creatures such as bacteria, fungi, and plants (Duan et al., 2015). Bacillus subtilis (Sundaram et al., 2012), Penicillium