Trauma/Reconstruction/Diversion Pregnancy and Delivery in Women with Lower Urinary Tract Reconstruction: A National Multicenter Retrospective Study from the French-Speaking Neuro-Urology Study Group (GENULF) and the Neuro-Urology Committee of the French Association of Urology E. Bey,* Q. Manach, B. Peyronnet, A. Even, E. Chartier Kastler, R. Walder, A. Ruffion, M. Baron, A. Charlanes, X. Biardeau, V. Quenneville, B. Boillot, C. Duport, T. Tricard, C. Saussine, X. Game, G. Capon, J. Kerdraon, J. N. Cornu, C. Garabedian, L. Le Normand, B. Perrouin-Verbe, V. Phe and M. A. Perrouin-Verbe From the Department of Urology (EB, LLN, MAP-V), Ho ˆ tel-Dieu Hospital, University of Nantes, Nantes, France, Department of Urology (QM, ECK, VP), Pitie-Salpetri ere Academic Hospital, Paris 6 University, Paris, France, Department of Urology (BP), University of Rennes, Rennes, France, Department of Neuro-Urology and of Physical Medicine and Rehabilitation (AE), Raymond Poincare Hospital, Garches and Versailles Saint-Quentin en Yvelines University (AE), Versailles, France, Gynecology and Obstretrics Department (RW), Croix-Rousse Hospital, University of Lyon, Lyon, France, Department of Urology (AR), Lyon Sud Hospital-Pierre-Benite, University of Lyon, Lyon, France, Department of Urology (MB, JNC), University of Rouen, Rouen, France, Department of Physical Medicine and Rehabilitation (AC), Tenon Academic hospital, Paris 6 University, Paris, France, Department of Urology (XB), University of Lille, Lille, France, Department of Urology (VQ), Boulogne-Billancourt Hospital, Paris, France, Department of Urology University of Grenoble (BB), Grenoble, France, Department of Urology (CD), University of Dijon, Dijon, France, Department of Urology (TT, CS), University of Strasbourg, Strasbourg, France, Department of Urology (XG), Rangueil Hospital, University of Toulouse, Toulouse, France, Department of Urology (GC), University of Bordeaux, Bordeaux, France, Department of Physical Medicine and Rehabilitation of Kerpape (JK), Ploemeur, France, Department of gynecology and obstetrics (CG), University Hospital of Lille, Lille, France, and Department of Physical Medicine and Rehabilitation (BP-V), Saint-Jacques Hospital, University of Nantes, Nantes, France Purpose: Management of pregnancy and delivery in women with lower urinary tract reconstruction is challenging and the currently available literature is insufficient to guide clinical practice. We report pregnancy and delivery out- comes in this specific population. Materials and Methods: We conducted a national multicenter retrospective study (16 centers) including 68 women with 96 deliveries between 1998 and 2019. These women had at least 1 successful pregnancy and delivery after augmentation enterocystoplasty, catheterizable channel creation and/or artificial urinary sphincter implantation. Maternal and fetal complications during pregnancy and delivery were reported, as well as postpartum functional outcomes, according to the delivery mode. The chi-square test and Student’s t-test were used to compare categorical and continuous variables, respectively. Results: Overall 32% of reported pregnancies were complicated by febrile urinary tract infections, 13.5% by renal colic and 14.6% required upper urinary tract diversion. In addition, 10% of patients reported transient self-catheterization difficulties and 13.5% reported de novo or increased urinary incontinence. The preterm delivery rate was 35.3%. Elective C-section was performed in 61% of pregnancies. Twenty complications occurred during delivery (20%), including 19 during elective C-section. Urinary continence at 1 year was unchanged for 93.5% Accepted for publication June 18, 2020. No direct or indirect commercial, personal, academic, political, religious or ethical incentive is associated with publishing this article. * Correspondence: Department of Urology, CHU-Universite de Nantes, 1 place Alexis Ricordeau, 44000 Nantes, France (telephone: þ33673358799; FAX: þ33220083922; email: Elsa.bey88@gmail.com ). Editor’s Note: This article is the third of 5 published in this issue for which category 1 CME credits can be earned. Instructions for obtaining credits are given with the questions on pages 1391 and 1392. Abbreviations and Acronyms AE [ augmentation enterocystoplasty AUS [ artificial urinary sphincter CCC [ catheterizable channel creation LUTR [ lower urinary tract reconstruction SCI [ spinal cord injury UTI [ urinary tract infection WA [ weeks of amenorrhea 0022-5347/20/2046-1263/0 THE JOURNAL OF UROLOGY ® Ó 2020 by AMERICAN UROLOGICAL ASSOCIATION EDUCATION AND RESEARCH,INC. https://doi.org/10.1097/JU.0000000000001233 Vol. 204, 1263-1269, December 2020 Printed in U.S.A. www.auajournals.org/jurology j 1263 Copyright © 2020 American Urological Association Education and Research, Inc. Unauthorized reproduction of this article is prohibited.