REVIEW ARTICLE Implementation of a Nationwide Strategy for the Prevention, Treatment, and Rehabilitation of Cardiovascular Disease ‘‘ATodo Coraz on’’ Gabriela Borrayo Sanchez, a Mart  ın Rosas Peralta, b Olga Georgina Mart  ınez Monta~ nez, c Samuel Justiniano Cordero, d German Fajardo Dolci, e Ana Carolina Sepulveda Vildosola, f and Jesus Arriaga D avila g a Programa ‘‘ATodo Corazon’’, Centro M edico, Nacional, Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de M exico, M exico b  Area de Proyectos Especiales del Programa ‘‘ATodo Corazon’’, Centro M edico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de M exico, M exico c Programa ‘‘A Todo Corazon’’, Direcci on de Prestaciones M edicas, Instituto Mexicano del Seguro Social, Ciudad de M exico, M exico d  Area de Diagn ostico y Tratamiento, Instituto Mexicano del Seguro Social, Ciudad de M exico, M exico e Facultad de Medicina, Universidad NacionalAut onoma de M exico, Ciudad de M exico, M exico f Unidad de Investigaci on, Educaci on y Politicas en Salud, Centro M edico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de M exico, M exico g Direcci on de Prestaciones M edicas, Instituto Mexicano del Seguro Social, Ciudad de M exico, M exico Received for publication March 28, 2018; accepted December 6, 2018 (ARCMED-D-18-00179). The cardiovascular diseases (CVDs) have a growing impact over the world mortality, affecting mostly low and middle-income countries. This is due to changes in the popula- tion pyramid and the increase in unhealthy lifestyles that predispose the global population to cardiovascular risk factors such as overweight, obesity, smoking, hypertension, dia- betes, dyslipidemias and metabolic syndrome. Ischemic heart disease and the cerebral vascular event remain the first causes of death reported by the World Health Organization (WHO) for more than a decade. Mexico has high prevalence in obesity, overweight, hy- pertension and diabetes in the population over 20 years old; Within the OECD countries (Organization for Economic Cooperation and Development) are the country with the highest mortality due to acute myocardial infarction over 45 years in the first 30 days. In order to face the growing pandemic of CVDs, the IMSS, it has developed and imple- mented a comprehensive care program called ‘‘ATodo Corazon’’, it is the first program of integral care which seeks to strengthen the actions to improving the impact of CVDs from health. This review is focused on describing the 7 axes that make up the program; each axe is described in detail. Axes one to three are dedicated to promotion and primary pre- vention of CVDs. Axes 4 and 5 are dedicated to infarction code, as a national strategy to confront the principal cause of death in Mexico. Finally axes 6 and 7 are dedicated to intensive care, secondary prevention and rehabilitation of CVDs. Ó 2018 IMSS. Published by Elsevier Inc. Key Words: Health promotion, Cardiovascular disease, Prevention, Risk calculator, Acute myocardial infarction, Rehabilitation, IMSS, Mexico. Cardiovascular diseases (CVDs) including the strokes are the leading cause of death worldwide. World Health Orga- nization (WHO) reported 15 million deaths in 2015 (1). In Mexico, the INEGI (National Institute of Statistics and Geography) reported 175,078 deaths due to cardiovascular disease in 2016 (2), indeed in the last three decades has become the leading cause of death. The main underlying cause is acute myocardial infarction. Mexico has been considered one of the countries with the highest critical increased mortality in patients over 45 years old by the Organization for Economic Cooperation and Development (OECD) since 2013 (Figure 1), which persists in the latest Address reprint requests to: Gabriela Borrayo Sanchez, Comisionada del Programa ‘‘ATodo Corazon’’, Centro M edico, Nacional, Siglo XXI, Instituto Mexicano del Seguro Social, Av. Cuauhtemoc 330, Col. Doctores, Del. Cuauhtemoc, 06720, Ciudad de M exico, M exico; Phone: (þ52) (55) 1200-4002; E-mail: gborrayos@yahoo.com.mx or gabriela.borrayo@imss. gob 0188-4409/$ - see front matter. Copyright Ó 2018 IMSS. Published by Elsevier Inc. https://doi.org/10.1016/j.arcmed.2018.12.007 Archives of Medical Research - (2018) -