TOOLS FOR ADVANCING PHARMACY PRACTICE Journal of the American Pharmacists Association www.japha.org Nov/Dec ฀2012฀•฀52:6฀•฀ JAPhA • e231 John A. Sauceda is a PhD candidate in health psychology, Department of Psychol- ogy, University of Texas at El Paso. Amanda M. Loya, PharmD, is Clinical Assistant Pro- fessor; and Jeri J. Sias, PharmD, MPH, is Clinical Associate Professor, University of Texas at El Paso/University of Texas at Austin Cooperative Pharmacy Program with the University of Texas at El Paso Col- lege of Health Sciences and the University of Texas at Austin College of Pharmacy, Aus- tin. Thomas Taylor, PhD, is Statistician, Defense Language Institute and Foreign Language Center, Monterey, CA. John S. Wiebe, PhD, is Associate Professor, Depart- ment of Psychology, University of Texas at El Paso. José O. Rivera, PharmD, is Clini- cal Professor, University of Texas at El Paso/ University of Texas at Austin Cooperative Pharmacy Program with the University of Texas at El Paso College of Health Sciences and the University of Texas at Austin College of Pharmacy. Correspondence: John A. Sauceda, De- partment of Psychology, University of Texas at El Paso, 500 W. University Ave., El Paso, TX 79902. E-mail: jasauceda@miners.utep. edu Disclosure: None. Acknowledgments: To Barry Weiss, MD; Veronica Rudder, BSPharm; Margie E. Perez, PharmD; and José C. Rodriguez, CPhT. To research assistants Ivan Reveles, PharmD; Jennifer Hernandez, PharmD; Megan Chil- son, PharmD; Christina Molina, PharmD; Judit Valdiviez, PharmD; and Denise Pinal, PharmD. To expert panel members Ulysses Urquidi, MD; Charmaine Martin, MD; Oralia Bazaldua, PharmD; Jenny Splawn, PharmD; Jane Poss, PhD: Lourdes Cuellar, BSPharm; Libby Berkeley; Andres Muro; Melissa Agu- irre; Emilio Saenz; and Esperanza Vasquez. Funding: 2007–08 Health Literacy Initiative, Paso del Norte Health Foundation, El Paso, TX. Previous presentation: 67th Annual U.S.– Mexico Border Health Association Confer- ence, El Paso, TX, June 4, 2009. Received September 8, 2011, and in revised form December 16, 2011. Accepted for publi- cation March 24, 2012. Abstract Objective: To evaluate the psychometric properties of a newly developed Medi- cation Literacy Assessment in Spanish and English (MedLitR x SE). Design: Descriptive, nonexperimental, cross-sectional study. Setting: El Paso, TX, from December 2006 to June 2009. Participants: 181 English- or Spanish-speaking adults. Intervention: Survey administered in two phases. Main outcome measures: Descriptive statistics, internal consistency, confir- matory factor analysis (CFA) and fit indices, and criterion-related validity. Results: The 20-item MedLitR x SE tool showed adequate internal consistency and reliability, and CFA revealed overall good model fit. In phase 2, the shorter 14-item MedLitR x SE showed good total test reliability and correlated well with the Short Test of Functional Health Literacy in Adults. Item response theory analyses showed no language bias and a one-dimensional (i.e., one factor) model of medication literacy. Conclusion: The initial and latest shorter version of the MedLitR x SE tool demon- strated good psychometric properties. This tool may provide a new option to assess “medication literacy” in English and Spanish. Keywords: Health literacy, medication literacy, Spanish patients, psychometric evaluations. J Am Pharm Assoc. 2012;52:e231–e240. doi: 10.1331/JAPhA.2012.11264 Medication literacy in Spanish and English: Psychometric evaluation of a new assessment tool John A. Sauceda, Amanda M. Loya, Jeri J. Sias, Thomas Taylor, John S. Wiebe, and José O. Rivera