SUBMITTED 26 JAN 21 REVISION REQ. 31 MAR 21; REVISION RECD. 8 APR 21 ACCEPTED 27 APR 21 ONLINE-FIRST: MAY 2021 DOI: https://doi.org/10.18295/squmj.5.2021.101 Prevalence of Celiac Disease in Omani Adults with Iron Deficiency Anemia of Unknown Cause A case-finding study Safa Ambusaidi, 1 Al Manar Al Busaidi, 1 Asma Al Salmani, 2 Robin Davidson, 3 Jalila Al Shekaili, 4 Mahmood Al Kindi, 4 *Rahma Al Kindi 2 1 Oman Medical Specialty Board, Muscat, Oman; Departments of 2 Family Medicine & Public Health, 4 Microbiology & Immunology, Sultan Qaboos University Hospital, Muscat, Oman; 3 Department of Family Medicine & Public Health, University of Bristol, Bristol, United Kingdom. *Corresponding Author’s e-mail: rkindi@squ.edu.om Abstract Objectives: This study aimed to estimate the serological prevalence of celiac disease in patients with IDA of unknown cause at primary health care facility. Methods: This is a prospective case finding study that was conducted at the primary care clinics in the Sultan Qaboos University Hospital (SQUH) from September 2018 to June 2020. A total of 104 patients aged 18 to 55 years old, with a hemoglobin (Hb) level less than 11.5 g/dl for males and less than 11.0 g/dl for females and a ferritin level less than 30 ng/mL for males and less than 13 ng/mL for females participated in the study. Blood samples were obtained for an initial serological screen using serum IgA level and then those with normal level of IgA, had IgA- Anti-tissue transglutaminase antibody (tTG) and IgA- anti-deamidated gliadin peptide (DGP). Positive IgA-tTG test was confirmed using IgA-endomysial antibodies. Patients with low IgA level were tested using IgG-