Uysal et al. J Hypertens Manag 2017, 3:027 Volume 3 | Issue 1 DOI: 10.23937/2474-3690/1510027 Open Access ISSN: 2474-3690 Journal of Hypertension and Management Citaton: Uysal B, Donmez O, Uysal F (2017) Hypertension in Children: A Single Center Experience. J Hypertens Manag 3:027. doi.org/10.23937/2474-3690/1510027 Received: July 24, 2017: Accepted: August 29, 2017: Published: August 31, 2017 Copyright: © 2017 Uysal B, et al. This is an open-access artcle distributed under the terms of the Creatve Commons Atributon License, which permits unrestricted use, distributon, and reproducton in any medium, provided the original author and source are credited. • Page 1 of 6 • Uysal et al. J Hypertens Manag 2017, 3:027 Hypertension in Children: A Single Center Experience Berfn Uysal 1 , Osman Donmez 2 and Fahretn Uysal 3 * Abstract Backgrounds: Hypertension (HTN) in childhood is a seri- ous cause of mortality and morbidity Hypertension during childhood is diagnosed more than past as a consequence of increasing awareness about childhood hypertension, mea- suring blood pressure by the accurate technique and child- hood obesity epidemic. Aims: Demographic profles, treatment regimens, response to treatment and etiology of hypertension were reviewed in children diagnosed with hypertension in this study. Study design: Retrospective cross-sectional study. Methods: Children diagnosed with hypertension in our cen- ter between January 1, 2012 and December 31, 2013 was reviewed in this study. Results: The mean age of 231 patients diagnosed as hy- pertensive was 14.4 ± 4.5 at the time of diagnosis. One hun- dred seventeen patients (50.6%) were classifed as having primary hypertension and 49.4% of the patients were classi- fed as having secondary hypertension. Family history was present in 11.7% of the patients. Twenty patients with prima- ry hypertension had family history whereas 7 patients with secondary hypertension had family history; this difference was statistically signifcant (p = 0.01). There were 17 hy- pertensive children with chronic kidney disease and 20 re- nal transplantation patients were found to be hypertensive. End organ damage was found in 136 patients. Ninety four patients were advised life style changes, 60 patients were treated by calcium channel blockers, 22 patients by angio- tensin converting enzyme inhibitors, 19 patients by beta blockers and the rest of the patients by combined therapy. Treatment was effcient in 76.6% of the patients. Response to treatment did not differ between primary and secondary hypertension. There was no association between end organ damage and younger age at the time of diagnosis. ORIGINAL ARTICLE *Corresponding author: Fahretn Uysal, Department of Pediatric Cardiology, University of Uludag, Bursa, Turkey, E-mail: fahretn_uysal@mynet.com 1 Department of Pediatric Nephrology, Dortcelik Children’s Hospital, Bursa, Turkey 2 Department of Pediatric Nephrology, University of Uludag, Bursa, Turkey 3 Department of Pediatric Cardiology, University of Uludag, Bursa, Turkey Introducton Hypertension (HT) is a major risk factor for cardiac, cerebral, and vascular diseases that develop in the later years of life, although its origins can ofen be traced back to childhood. Compared to the adults, the prevalence of HT is lower among children (1 to 2%). However, the inci- dence of primary HT has been gradually increasing due to several factors such as the routne measurement of blood pressure in the outpatent clinics, obesity result- ing from the excessive consumpton of foods with high calorie and fat content, increased consumpton of salt, reduced physical actvity, and increasing stress [1,2]. Examinaton of the end-organ damage is important for making a decision on treatment, predictng progno- sis, and assessing the degree of HT. The relatonship between HT and development of ath- erosclerosis during adolescence has been demonstrated in autopsy studies [3]. Other indicators of end-organ damage Conclusion: Our study results highlighted the need for more detailed studies to investigate the main causes of sec- ondary HT in younger hypertensive children and also sug- gested that children with a family history of HT should be monitored closely. Assessment of the end-organ damage is also of utmost importance for diagnosis, follow-up, and the evaluation of treatment options. It is also emphasized that monotherapy should be initiated in patients who are unre- sponsive to the dietary changes, who have secondary HT, and who exhibit end-organ damage. Keywords Hypertension, Children, Etiology, End-organ damage