Accepted Manuscript Title: Molecular pathway activation – new type of biomarkers for tumor morphology and personalized selection of target drugs Authors: Anton Buzdin, Maxim Sorokin, Andrew Garazha, Marina Sekacheva, Ella Kim, Nikolay Zhukov, Ye Wang, Xinmin Li, Souvik Kar, Christian Hartmann, Amir Samii, Alf Giese, Nicolas Borisov PII: S1044-579X(18)30043-9 DOI: https://doi.org/10.1016/j.semcancer.2018.06.003 Reference: YSCBI 1484 To appear in: Seminars in Cancer Biology Received date: 3-5-2018 Revised date: 19-6-2018 Accepted date: 19-6-2018 Please cite this article as: Buzdin A, Sorokin M, Garazha A, Sekacheva M, Kim E, Zhukov N, Wang Y, Li X, Kar S, Hartmann C, Samii A, Giese A, Borisov N, Molecular pathway activation – new type of biomarkers for tumor morphology and personalized selection of target drugs, Seminars in Cancer Biology (2018), https://doi.org/10.1016/j.semcancer.2018.06.003 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.