PROOF
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ORIGINAL ARTICLE
Research ethics committee approval as reported for
abstracts submitted to the annual Euroanaesthesia
meeting
Paul McConnell, Nechama Kaufman, Stefan De Hert, Marc C. Samama,
Zsolt Molnar and Sharon Einav
BACKGROUND The annual congress of the European So-
ciety of Anaesthesiology (ESA) is one of the largest anaes-
thesia congresses in the world and exhibits more than 1200
abstracts annually.
OBJECTIVES The aims of this study were to quantify the
frequency of inadequate evidence of ethical approval for
abstracts submitted to the ESA congress and to examine
whether abstracts without appropriate ethical approval were
subsequently accepted.
DESIGN AND SETTING All abstracts submitted in 2015
were adjudicated according to European ethical criteria.
MAIN OUTCOME MEASURE The proportion of submitted
abstracts that lacked evidence of appropriate ethics com-
mittee approval. Secondary outcomes included the pro-
portion of accepted abstract that lacked evidence of
appropriate ethical approval; the proportion of correctly
identified case reports; the proportion of accepted abstracts
that lacked evidence of appropriate ethics committee
approvals corresponding to location (within/outside Europe);
and the proportion of accepted abstracts that lacked evi-
dence of appropriate ethics committee approvals corre-
sponding to a specific area of research.
RESULTS In total, 1792 abstracts were reviewed and 1572
(87.7%) involved humans. In 527 (29.4%), the authors failed
to demonstrate adequate ethical approval with higher rates in
abstracts submitted from Europe (32.1%) than the rest of the
world (23.5%), P < 0.001. Appropriate approvals were
reported in 80% of animal studies, 74.6% of case reports
and 57.6% of human research studies. The proportion with
evidence of adequate ethical approvals was lowest in ob-
stetric anaesthesia and emergency medicine. Case reports
were identified correctly 98.6% (347/352) of the time, but
14 research abstracts were assigned wrongly to this cate-
gory. Most abstracts (68.5%, 361/527) lacking evidence of
ethical approval were still accepted for presentation.
CONCLUSION Research abstracts lacking evidence of ap-
propriate ethical approval are common worldwide. Societies
shoulder the responsibility for ensuring that only ethically
sound abstracts are presented at meetings. Abstract sub-
mission systems must include mechanisms to ensure that
publications are accepted and judged not just on scientific
merit but also on adherence to best ethical practice.
Published online xx month 2017
Introduction
The annual congress of the European Society of Anaes-
thesiology (ESA) is one of the largest anaesthesia con-
ferences in the world, routinely hosting in excess of 6000
delegates. In addition to a full educational programme,
the conference offers the opportunity for researchers
from all over the world to present their research results.
All research submitted should be conducted in accor-
dance with the Declaration of Helsinki,
1
with appropriate
oversight and review from an institutional review board
(IRB)/research ethics committee where applicable.
Eur J Anaesthesiol 2017; 34:1–7
From the Department of Anaesthesia and Intensive Care Medicine, Royal Alexandra Hospital, Paisley, UK (PMc), the Intensive Care Unit, Shaare Zedek Medical Center,
Jerusalem, Israel (NK), the Department of Anaesthesiology, Ghent University Hospital, Ghent University, Ghent, Belgium (SDH), the Department of Anaesthesiology, Cochin
and Ho ˆ tel-Dieu University Hospitals, Paris Descartes University, Paris, France (MCS), the Department of Anaesthesiology and Intensive Therapy, University of Szeged,
Szeged, Hungary (ZM), and the Department of Anaesthesia and Intensive Care, Shaare Zedek Medical Center and Hebrew University Faculty of Medicine, Jerusalem, Israel
(SE)
Correspondence to Sharon Einav, MD, Director Surgical Intensive Care Unit, Shaare Zedek Medical Centre affiliated with the Hebrew University, P.O. Box 3235,
Jerusalem 91031, Israel
Tel: +972 2 6666664; fax: +972 2 6555144; e-mail: einav_s@szmc.org.il
0265-0215 Copyright ß 2017 European Society of Anaesthesiology. All rights reserved. DOI:10.1097/EJA.0000000000000669