___________________________________________________________________________________________ *Corresponding author: Email: bhagatne@umdnj.edu; British Journal of Medicine & Medical Research 3(4): 1380-1387, 2013 SCIENCEDOMAIN international www.sciencedomain.org Gender Disparities in Open Globe Injuries: Ten- Year Review of an Urban Population Parisa Emami-Naeini 1 , Alain M. Bauza 1 , Paul D. Langer 1 , Marco A. Zarbin 1 and Neelakshi Bhagat 1* 1 The Institute of Ophthalmology and Visual Science, New Jersey Medical School, Doctors Office Center, Suite 6100, Newark, NJ 07101-1709. Authors’ contributions This work was carried out in collaboration between all authors. Author PEN wrote the first draft of the manuscript and performed data analysis; author AMB performed data collection; authors PDL and MAZ revised the manuscript and reviewed the literature, author NB performed part of data collection, designed the study, analysed the data, revised and wrote the final manuscript and reviewed the literature. All authors read and approved the final manuscript. Received 18 th February 2013 Accepted 5 th April 2013 Published 23 rd April 2013 ABSTRACT Aims: To characterize gender differences in the ophthalmic findings and clinical outcomes of patients with open globe (OG) injuries. Study Design: Retrospective case series. Place and Duration of Study: Department of Ophthalmology, University Hospital, New Jersey Medical School between January 2001 and June 2010. Methodology: The medical records of all patients presenting with OG injuries to University Hospital, Newark, NJ from January 1, 2001 through June 30, 2010 were reviewed. Demographics, characteristics of the trauma, ophthalmic findings, and outcomes were compared in male and female patients. Results: A total 603 eyes (602 patients) with OG injuries were identified. Most of the patients (76.4%) were male. The mean patient age was 39.14 years which was significantly lower in males (35.66 years vs. 50.43 years in females; p<0.001). The vast majority of injuries were penetrating and/or work-related in men, whereas fall-related ruptures comprised the most common pattern of injury in women. Zone I was the most commonly injured zone in both genders, and Zone III wounds were more commonly seen Research Article