ARTICLE IN PRESS
G Model
Med Clin (Barc). 2017;xxx(xx):xxx–xxx
www.elsevier.es/medicinaclinica
Original article
Short-term reconsultation, hospitalisation, and death rates after
discharge from the emergency department in patients with acute
heart failure and analysis of the associated factors. The ALTUR-ICA
Study
Òscar Miró
a
, Víctor Gil
a
, Francisco Javier Martín-Sánchez
b
, Pablo Herrero
c
, Javier Jacob
d
,
Carolina Sánchez
a
, Carolina Xipell
a
, Sira Aguiló
a
, Pere Llorens
e,∗
, on behalf of the ICA-SEMES group
♦
a
Grupo de Investigación «Urgencias: Procesos y Patologías», Área de Urgencias, Hospital Clínic, Institut D’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de
Barcelona, Barcelona, Spain
b
Servicio de Medicina Preventiva, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Universidad Complutense de Madrid,
Madrid, Spain
c
Servicio de Urgencias, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
d
Servicio de Urgencias, Hospital Universitario de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
e
Servicio de Urgencias, Corta Estancia y Hospitalización a Domicilio, Hospital General de Alicante, Departamento de Medicina Clínica, Universidad Miguel Hernández, Instituto de
Investigación Sanitaria y Biomédica de Alicante (ISABIAL-FISABIO), Alicante, Spain
a r t i c l e i n f o
Article history:
Received 23 January 2017
Accepted 8 June 2017
Available online xxx
Keywords:
Acute heart failure
Death
Reconsultation
Hospitalisation
Accident and emergency
a b s t r a c t
Background and objectives: The aim of this study was to define the following in patients with acute heart
failure (AHF) discharged directly from accident and emergency (A&E): rates of reconsultation to A&E and
hospitalisation for AHF, and all-cause death at 30 days, rate of combined event at 7 days and the factors
associated with these rates.
Patients and method: The study included patients consecutively diagnosed with AHF during 2 months
in 27 Spanish A&E departments who were discharged from A&E without hospitalisation. We collected
43 independent variables, monitored patients for 30 days and evaluated predictive factors for adverse
events using Cox regression analysis.
Results: We evaluated 785 patients (78 ± 9) years, 54.7% women). The rates of reconsultation, hospitalisa-
tion, and death at 30 days and the combined event at 7 days were: 26.1, 15.7, 1.7 and 10.6%, respectively.
The independent factors associated with reconsultation were no endovenous diuretics administered in
A&E (HR 2.86; 95% CI 2.01–4.04), glomerular filtration rate (GFR) < 60 ml/min/m
2
(1.94; 1.37–2.76) and
previous AHF episodes (1.48; 1.02–2.13); for hospitalisation these factors were no endovenous diuret-
ics in A&E (2.97; 1.96–4.48), having heart valve disease (1.61; 1.04–2.48), blood oxygen saturation at
arrival to A&E < 95% (1.60; 1.06–2.42); and for the combined event no endovenous diuretics in A&E (3.65;
2.19–6.10), GFR < 60 ml/min/m
2
(2.22; 1.31–3.25), previous AHF episodes (1.95; 1.04–3.25), and use of
endovenous nitrates (0.13; 0.02–0.99).
Conclusion: This is the first study in Spain to describe the rates of adverse events in patients with AHF
discharged directly from A&E and define the associated factors. These data should help establish the most
adequate approaches to managing these patients.
© 2017 Elsevier Espa ˜ na, S.L.U. All rights reserved.
Please cite this article as: Miró Ò, Gil V, Martín-Sánchez FJ, Herrero P, Jacob J, Sánchez C, et al. Tasas de reconsulta, hospitalización y muerte a corto plazo
tras el alta directa desde Urgencias de pacientes con insuficiencia cardiaca aguda y análisis de los factores asociados. Estudio ALTUR-ICA. Med Clin (Barc). 2017.
https://doi.org/10.1016/j.medcli.2017.06.004
∗
Corresponding author.
E-mail address: llorens ped@gva.es (P. Llorens).
♦
The other members of the ICA-SEMES group are listed in Appendix A.
2387-0206/© 2017 Elsevier Espa ˜ na, S.L.U. All rights reserved.
MEDCLE-4147; No. of Pages 11