92 Published by Indonesia Journal of Biomedical Science | IJBS 2021; 15(1): 92-95 | doi: 10.15562/ijbs.v15i1.305 ORIGINAL ARTICLE The relationship of blood group, blood components, and the age of patients with the degree of transfusion reaction at Dr. Wahidin Sudirohusodo, Makassar, Indonesia Helena Sembai 1* , Raehana Samad 2,3 , Rachmawati Adiputri Muhiddin 2,4 , Mansyur Arif 2,4,5 1 Clinical Pathologist Education Program, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia 2 Department of Clinical Pathology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia 3 Blood Transfusion Technical Implementation Unit, South Sulawesi, Provincial Health Ofce, Indonesia 4 Clinical Pathology Laboratory, Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia 5 Clinical Pathology Laboratory, Universitas Hasanuddin Hospital, Makassar, Indonesia *Correspondence: Helena Sembai; Clinical Pathologist Education Program, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia; sembaihelena@gmail.com Indonesia Journal of Biomedical Science (IJBS) 2021, Volume 15, Number 1: 92-95 P-ISSN.2085-4773, E-ISSN.2302-2906 Received: 2021-03-25 Accepted: 2021-07-15 Published: 2021-07-30 92 Published by Indonesia Journal of Biomedical Science ABSTRACT Background: Transfusion is an additional therapy in the case of hematology and non-hematology. However, it can be detrimental due to its side efects ranging from mild to severe reactions. This study aimed to determine the relationship of blood types, blood components, and the age of patients with the degree of transfusion reaction. Methods: A retrospective study with secondary data of the patients experiencing transfusion reactions was conducted from January 2017 to December 2019. The population included all patients receiving a transfusion of blood products. The sample met the inclusion criteria, such as the medical records of patients who experienced transfusion reactions during and after the transfusion. The exclusion criteria were cryoprecipitate blood components. Data were analyzed using SPSS version 20 for Windows. Results: Among 228 subjects, there were a higher number (52.60%) of females than males (47.40%). The majority of patients ranged within 40-59 years old (52.70%). Most blood types were O (53.00%), while the dominant blood component was PRC (packed red cell) (50.30%). There was no signifcant relationship between blood types, blood components, and the age of patients with the degree of transfusion reaction (p>0.05). Conclusion: There was no signifcant relationship between blood types, blood components, and the age of patients with the degree of transfusion reaction. Keywords: Transfusion, Blood Group, Blood Components, Transfusion Reactions Cite this Article: Sembai, H., Samad, R., Muhiddin, R.A., Arif, M. The relationship of blood group, blood components, and the age of patients with the degree of transfusion reaction at Dr. Wahidin Sudirohusodo, Makassar, Indonesia. IJBS 15(1): 92-95. DOI: 10.15562/ijbs.v15i1.305 Open access: http://ijbs-udayana.org/ INTRODUCTION Blood transfusion is an important adjunctive therapy for diagnosing disorders in the feld of hematology and non-hematological cases such as sepsis, preoperative preparation, or other diseases. 1,2 Te goals of blood transfusions include restoring blood volume to normal, replacing defciencies in blood components, and increasing oxygenation and hemostasis. 1 One of the important steps that must be performed is a routine serological test at a blood bank to ensure that the transfusion recipient gets the appropriate blood and hemolytic transfusion reactions are prevented. Pretransfusion tests such as ABO, Rhesus blood groups, and cross-match between the recipient’s blood and donor blood must be performed. 1,2 In addition to its efciency and low- cost properties, the primary indication for the use of blood components can also minimize transfusion reactions. 3 Transfusion reactions include mild, moderate, and severe reactions. Given its strategic function, blood transfusions should be carried out carefully and the side efects must always be considered along with the benefts. 3 Blood transfusions can cause adverse events due to side efects such as hemolytic reactions, fever, allergic reactions, transfusion-related acute lung injury (TRALI), infectious diseases through blood transfusions, and carcinogenic spread. Terefore, the indication for allogeneic blood transfusion should be tightened by considering these things. 3,4 Research conducted by Okoroiwu IL et al. in several transfusion centers in Owerri Imo - Nigeria, for 32 weeks showed that the highest incidence of transfusion reactions was reported in 53.33% (16 cases) of blood group O, 26.67% (8 cases) of blood group A, and 6.67% (2 cases) group blood B in a total of 5550 transfusions. 5 Transfusion