_____________________________________________________________________________________________________ *Corresponding author: E-mail: hkamal2000@gmail.com; British Journal of Applied Science & Technology 16(3): 1-9, 2016, Article no.BJAST.26683 ISSN: 2231-0843, NLM ID: 101664541 SCIENCEDOMAIN international www.sciencedomain.org Structural Investigations on Na 2 O – CaO-V 2 O 5 - SiO 2 Bioglass Ceramics G. El-Damrawi 1 , A. K. Hassan 1 , H. Kamal 1* , M. Aboelez 2 and S. Labeeb 1 1 Department of Physics, Faculty of Science, Mansoura University, Mansoura 35516, Egypt. 2 Faculty of Engineering, Shebin El Kom University, Egypt. Authors’ contributions This work was carried out in collaboration between all authors. Authors GED and HK designed the study, performed the statistical analysis, wrote the protocol, wrote the first draft of the manuscript and managed literature searches. Authors AKH, MA and SL managed the analyses of the study and literature searches. All authors read and approved the final manuscript. Article Information DOI: 10.9734/BJAST/2016/26683 Editor(s): (1) Luigi Maxmilian Caligiuri, Faculty of Science, University of Calabria, Italy AND Foundation of Physics Research Center (Director)- FoPRC, Italy. Reviewers: (1) Alexandre Gonçalves Pinheiro, Ceará State University, Brazil. (2) C. Nyamhere, Midlands State University, Zimbabwe. Complete Peer review History: http://sciencedomain.org/review-history/14814 Received 28 th April 2016 Accepted 21 st May 2016 Published 30 th May 2016 ABSTRACT All as obtained glasses in the system 24.5 Na 2 O-24.5 CaO-6 P 2 O 5 - xV 2 O 5 (45-x) SiO 2 (x ranges from 0-15 mole %) are transparent and have an amorphous network structure. Glasses containing up to 6 mol% V 2 O 5 still transparent upon heat treatment at 660°C for 4 hours. On the other hand, heat sintered glasses containing higher V 2 O 5 concentration are transformed to opaque white glass ceramic characterized by their highly crystalline network structure. Crystalline apatite (calcium phosphate, Ca 3 (PO 4 ) 2 ), wollastonite (calcium silicate, CaSiO 3 ), and sodium vanadate (Na 2 VO 3 ) are the main well-formed crystalline species played the major role in material bioactivity. The advantage of V 2 O 5 containing glasses is that it can easily be crystallized, since the high crystallinity is obtained by lowering sintering temperature when compared with that of glasses free from V 2 O 5 . Crystalline clusters containing vanadate species and both apatite and wollastonite phases are evidenced to be present. A hydroxyapatite (HA) formation is confirmed by the in vitro test of bioactivity. Processes of degradation and ion exchange between sample and phosphate solution and HA precipitation are evaluated. It is found that V 2 O 5 can speed up the rate of reaction between the tested sample and phosphate solution. Glass ceramics containing V 2 O 5 is highly active than that of vanadium free silicate glasses. Original Research Article