Volume 3 • Issue 3 • 1000136 J Anal Bioanal Techniques ISSN:2155-9872 JABT, an open access journal Open Access Letter Pandey et al., J Anal Bioanal Techniques 2012, 3:3 DOI: 10.4172/2155-9872.1000136 Introduction Modern era of “Genomic Revolution” has led to the exploration of various domains of “omics” i.e. genomics, proteomics, transcriptomics etc. and transformed our vision and understanding of the dynamic interaction between living organisms and the corresponding environment. Genomics is considered as study of genome of organisms and has its wide applications in almost all areas of biology, including drug discovery and in proteomic analysis [1-6]. It helps in obtaining the blue print of an organism and further enables to understand their organization and functions. Applied genomics has two major aspects: i) efforts to determine the DNA sequence of organisms as well as physical mapping, ii) expression of genes to describe their function and interaction (functional genomics). With the advent of advanced computational techniques, a new branch has now emerged and termed as “comparative genomics” which deals with relationship between genomes of different species. Promising Areas of Genome Research If we analyze the potential areas of genome research, the first and foremost is sequencing the genomes of model organisms. e race of DNA sequencing started with complete sequencing of bacteriophage φ-X174 in 1977 by Fredrick Sanger using Sanger method of DNA sequencing and moved on with sequencing of Haemophilus influenzae in 1995 and then many more model organisms like E.coli, Bacillus subtilis, Saccharomyces cerevisiae, Arabidopsis thaliana, Caenorhabditis elegans, Drosophila melanogaster etc [7,8]. e whole genome sequencing of model organisms provided a valuable insight into the molecular keys behind their growth, development and function mechanism. e knowledge of genome has opened a wide range of possibilities in elucidating the future prospects of gene regulation mechanism, trends in molecular evolution and phylogeny, genome organisation and in pharmaceutical researches to very higher extent. ese possibilities can be practically observed for their usage in cancer therapeutics development and further in determining the structural and molecular aspects of the pathological disorders. Further, the application of genome sequencing methodologies can be used in the analysis of Saccharomyces cerevisiae and other yeast genomes that can help in development of new and improved strains of individual importance as well as can be helpful in search of novel anti fungal drugs. e advancement in the sequencing technologies has outfield the current genomic databases and has created a wide opportunity for biologist to explore and unravel the hidden patters and has lead to the evolution on whole new discipline termed as “functional genomics” [9]. is field mainly deals with dynamic aspects such as gene transcription, translation, protein-protein interaction etc. It mainly relates the genome of an organism with its phenotype and enables us to gain insights into genomic functionality and the associated phenotypic characteristics [9]. is branch has paved our way in solving the mysteries of the genome and furthermore, it helped in resolving the mysteries of life forms. Large amount of genomic data has revolutionised the arena of pharmaceutical researches. e genomic data not only enhanced our vision regarding the potential drug targets but has also provided us valuable information regarding drug metabolism and their associated positive and negative consequences in human body. It played a very crucial role in reducing the time constraints for drug development [1]. ese advancements further lead to the development of a promising area in the field of drug design and health care researches, and was termed as “personalised medicine”, believed to be a milestone in the area of pharmaceutical research [1]. It is well realised that there is an inter-individual variation with respect to therapeutic responses to most of drugs and the same applies with the adverse drug reactions. So, a personalized approach can be a promising approach to certain deadly diseases, although it has some limitations that are needed to be addressed. e advent of genomic era has further enhanced in the area of proteomic researches. e 3D confirmation of protein structures are required in order to resolve the ligand-target association mechanism [1-6]. e availability of genomic data’s has enabled us to carry a comparative screening of available structures that are closely associated to our model protein. ese approaches require a combination of computational genomics and biophysical approaches and are now considered as a central point of in-silico drug discovery. e Structural Genomics Consortium (SGC) that was launched with the aim of determining 3D structures of proteins having promising significance in the field of medicine, has further facilitated in target based drug therapy development [10]. e structural genomics not only reduced the efforts carried out by the researchers, forecasting their work in the field of *Corresponding author: Rituraj Purohit, Bioinformatics Division, School of Bio Sciences and Technology, Vellore Institute of Technology University, Vellore 632014, Tamil Nadu, India, Tel: 91-9944649073; E-mail: riturajpurohit@gmail.com Received June 10, 2012; Accepted July 02, 2012; Published July 07, 2012 Citation: Pandey A, Kumar A, Purohit R (2012) Current Vision of Genomic Research and Its Positive Impact on Global Community. J Anal Bioanal Techniques 3:136. doi:10.4172/2155-9872.1000136 Copyright: © 2012 Pandey A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Genomics has its own application in wide range of life science research. Recent studies are now being concentrated on functional and comparative aspects of genomics and that makes an efficient platform for drug discovery and pharmaceutical research. In this note, we have focused on how the genomic studies are showing their positive impact on the global community and in what way it could be further advanced. Current Vision of Genomic Research and Its Positive Impact on Global Community Akanksha Pandey, Ambuj Kumar and Rituraj Purohit* Bioinformatics Division, School of Bio Sciences and Technology, Vellore Institute of Technology University, Vellore 632014, Tamil Nadu, India Journal of Analytical & Bioanalytical Techniques J ou r n a l o f A n a l y t i c a l & B i o a n a l y t i c a l T e c h n i q u e s ISSN: 2155-9872