Host Modulation in the Management of Endodontic Periodontic Lesions - A Report of 3 Cases Afaf Zia 1 , Afshan Bey 2 , Syed Mukhtar-un-Nisar Andrabi 3 , Saif Khan 4 , Masood Khan 5 ABSTRACT: The present case series presents different patients with chief complaint of mobility in teeth where finally endo-perio involvement was seen. The endo-perio combined lesions generally show that there is communication between pulp and periodontal tissues because of common dental origin. Diagnosis in such cases is difficult and generally present problem in the management. All the cases were managed by non surgical endodontic therapy and host modulation was done. Local factors causing the lesion were removed. Clinical outcome after six and nine months were quite satisfactory. Combined endo-perio cases are challenging to the dentists and involve multidisciplinary involvement. To manage such cases, dentists have to rely on the unconventional techniques. Key words: combined endo perio lesions, host modulation, non surgical therapy CASE REPORT doi: 10.5866/2014.631637 1&4 Assistant Professor 2 Professor Department of Periodontology, Dr Z A Dental College, Aligarh Muslim University, Aligarh, India. 3 Assistant Professor, Department of Conservative and Endodontics, Dr Z A Dental College, Aligarh Muslim University, Aligarh, India. 5 Assistant Professor, Department of Oral Diagnosis & Oral Pathology, Dr Z A Dental College, Aligarh Muslim University, Aligarh, India. Article Info: Received: April 9, 2014 Review Completed: May 10, 2014 Accepted: June 12, 2014 Available Online: October, 2014 (www.nacd.in) © NAD, 2014 - All rights reserved Email for correspondence: afafzia@gmail.com Quick Response Code Introduction Combined endo-perio lesions are frequently encountered in dental clinics and are difficult to manage. Non surgical therapy like scaling and root planning and root canal therapy is the preferred choice of treatment. At times, surgical therapy like open flap debridement and regenerative techniques may be required. To overcome the need of surgery, a new therapy of host modulation is used nowadays. Host modulation is a recent concept where the pro- inflammatory mediators and destructive enzymes in the host are modified. Effective results have been seen when this therapy has been used in combination with the conventional techniques. 1 We report here three combined endo-perio lesions where host modulation therapy has been used along with the conventional technique. INDIAN JOURNAL OF DENTAL ADVANCEMENTS Journal homepage: www. nacd. in Indian J Dent Adv 2014; 6(3): 1637-1640