RESEARCH REPORT
Comparative Effectiveness
Research and Children With
Cerebral Palsy: Identifying a
Conceptual Framework and
Specifying Measures
Mary E. Gannotti, PT, PhD; Mary Law, OT (Reg Ont), PhD, FCAOT; Amy F. Bailes, PT, PhD, PC;
Margaret E. O’Neil, PT, PhD, MPH; Uzma Williams, BA; Briano DiRezze, OT (Reg Ont), PhD; Expert Panel*
Department of Physical Therapy (Dr Gannotti), College of Education, Nursing and Health Professions, University of
Hartford, West Hartford, Connecticut; CanChild Centre for Childhood Disability Research (Drs Law and DiRezze, and
Ms Williams) McMaster University, Hamilton, Ontario, Canada; Division of Occupational Therapy and Physical Therapy
(Dr Bailes), Cincinnati Children’s Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio; Physical
Therapy and Rehabilitation Sciences Department (Dr O’Neil), College of Nursing and Health Professions, Drexel
University, Philadelphia, Pennsylvania.
Purpose: A step toward advancing research about rehabilitation service associated with positive outcomes
for children with cerebral palsy is consensus about a conceptual framework and measures. Methods: A Delphi
process was used to establish consensus among clinicians and researchers in North America. Results: Directors
of large pediatric rehabilitation centers, clinicians from large hospitals, and researchers with expertise in
outcomes participated (N = 18). Andersen’s model of health care utilization framed outcomes: consumer
satisfaction, activity, participation, quality of life, and pain. Measures agreed upon included Participation and
Environment Measure for Children and Youth, Measure of Processes of Care, PEDI-CAT, KIDSCREEN-10, PROMIS
Pediatric Pain Interference Scale, Visual Analog Scale for pain intensity, PROMIS Global Health Short Form,
Family Environment Scale, Family Support Scale, and functional classification levels for gross motor, manual
0898-5669/110/2801-0058
Pediatric Physical Therapy
Copyright C 2016 Wolters Kluwer Health, Inc. and Section on Pediatrics of the American Physical Therapy Association
Correspondence: Mary E. Gannotti, PT, PhD, Associate Professor, Department of Rehabilitation Sciences, University of Hartford, West Hartford, CT 06117
(Gannotti@hartford.edu).
*Expert Panel: Connie Andrade, MBA, PT, Intermountain Primary Children’s Hospital, Salt Lake City, Utah; Anita Bagley, PhD, MPH, Shriners Hospital for
Children, Sacramento, California; Danielle Bellows, PT, MHS, C/NDT, PCS, Connecticut Children’s Medical Center, Hartford, Connecticut; Sheree Chapman
York, PT, DPT, PCS, Children’s of Alabama, Birmingham, Alabama; Laura Crooks, OTR/L, MHA, Seattle Children’s Hospital, Seattle, Washington; George
E. Gorton III, MS, CCRP, Shriners Hospital for Children, Springfield, Massachusetts; Donna Hurley, PT, DPT, Feinberg School of Medicine, Northwestern
University, Chicago, Illinois; Michelle Leiter, RN, Intermountain Primary Children’s Medical Center, Salt Lake, Utah; Mark Malczynski, PT, DPT, PCS,
Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania; Mary Jane Mulcahey, OTR/L, PhD, Thomas Jefferson University, Philadelphia, Pennsylvania;
Rebecca Reder, OTD, OTR/L, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio; David Scalzitti, PT, PhD, OCS, George Washington University,
Washington, DC; Joe Schreiber, PT, PhD, PCS, Chathman University, Pittsburg, Pennsylvania; Durga Shah, PT, DPT, PCS, Children’s Healthcare of Atlanta,
Atlanta, Georgia; Denise Watson, MHSc, KidsAbility, Waterloo, Ontario, Canada.
Grant Support: American Physical Therapy Association, Section on Pediatrics Planning Grant 2012-2014; University of Hartford Institute for Translation
Research; CanChild; Drexel University; Cincinnati Children Hospital Medical Center; University of Cincinnati Center for Translational Research for funding
and in-kind support for this project.
The authors declare no conflicts of interest.
DOI: 10.1097/PEP.0000000000000203
Copyright © 2016 Wolters Kluwer Health, Inc. and the Section on Pediatrics of the American Physical Therapy Association.
Unauthorized reproduction of this article is prohibited.
58 Gannotti et al Pediatric Physical Therapy