_____________________________________________________________________________________________________ *Corresponding author: E-mail: nesreensafwat2015@yahoo.com; J. Adv. Med. Med. Res., vol. 34, no. 24, pp. 244-249, 2022 Journal of Advances in Medicine and Medical Research Volume 34, Issue 24, Page 244-249, 2022; Article no.JAMMR.95170 ISSN: 2456-8899 (Past name: British Journal of Medicine and Medical Research, Past ISSN: 2231-0614, NLM ID: 101570965) Anthropometric Measures and IQ in Down Syndrome and Healthy Children: A Case Control Study Nesreen Safwat El-Feel a* , Heba El Sayed Dawoud a , Rasha Ahmed El-Shafey b , Ahmed Abdel Basset Abo El-Ezz a and Heba Saied El Mahdy a a Pediatrics Department, Faculty of Medicine, Tanta University, Tanta, Egypt. b Radiology Department, Faculty of Medicine, Tanta University, Tanta, Egypt. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JAMMR/2022/v34i244922 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/95170 Received: 20/10/2022 Accepted: 27/12/2022 Published: 29/12/2022 ABSTRACT Background: In humans, the most prevalent chromosomal disorder and most well-known cause of intellectual impairment is Down syndrome. Chromosome 21 trisomy is the main cause of it. This study’s goal was to compare anthropometric measures and intelligence quotient (IQ) in Down syndrome and healthy children. Methods: The study included 80 patients divided in to 2 groups: Group A patients: included Forty Down syndrome cases were recruited to the study, their age was between 6-15 years. Group B control: included Forty healthy children were enrolled to the study as a control group, their age and sex were matched with the Down syndrome group. Results: There were significantly lower in DS group than Controls group as regards height and height z-score. There were significantly higher in DS group than Controls group as regards mean Original Research Article