Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 10(8) pp. 207-212, August, 2022
Available online http://www.meritresearchjournals.org/mms/index.htm
Copyright © 2022 Author(s) retain the copyright of this article
Original Research Article
Use of Dental Medications During Lactation
Sandrine Ribeiro Amarante
1*
, Luana Martins Curcino
1
, Kássia Justo Coelho Margute Thiago Quirino
Mota da Silva
3
, Túlio Garcia Margute
4
, Max Soares Maione
5
, Andrei Rabenschlag Rossato
6
, Tiago
Garcia Margute
7
, Igor Fonseca dos Santos
8
Abstract
1
ULBRA, Palmas, TO, Brazil.
2
Department of Implantology, FACOP,
SP, Bauru, Brazil.
3
Department of Implantology, CEUMA,
MA, São Luis, Brazil.
4
Department of Phrostodontics, FACOP,
SP, Bauru, Brazil.
5
Medical student, Faculdade de Medicina,
UFT, Palmas/TO, Brazil.
6
Department of Implantology, São
Leopoldo Mandic, SP, Campinas, Brazil.
7
Department of Implantology, FACOP,
SP, Bauru, Brazil.
8
Department of Medicine and Dentistry,
UNIRG, Paraíso do Tocantins, CEULP-
ULBRA, IOA, Palmas, Tocantins, Brazil.
*Corresponding Author's E-mail:
tiagomargute@hotmail.com
Phone: +XX (48) 9 9919-9905
.
There has been a growing number of women who use drugs during breastfeeding,
with most of these drugs being compatible with this period. The objective of this
research was to correlate the use of dental medications with the lactation period, and
whether there were drugs passing through breast milk, as well as whether or not
mothers should stop breastfeeding when they are taking medication. Among the
drugs that were found, we highlight the antimicrobials, analgesics, local anesthetics,
benzodiazepines and tricyclic antidepressants. These being like the drugs of greater
consumption among the infants, according to the consulted literature. The study was
carried out by means of a literature review of August 2018, in June 2019 in which
articles were searched in Portuguese, Spanish, English language and books searched
in the library of the Lutheran University of Palmas. We searched databases such as
LILACS, ACADEMIC GOOGLE, PUBMED, LACTMED, and SCIELO, with
articles from the years 1988 to 2019. It was noticed that the drugs were mostly
compatible with breastfeeding, except that some drugs that have appeared in breast
milk in small quantities, others have not presented enough research, but that until
now are compatible with lactation.
Keywords: Breastfeeding, Lactation, Pharmacology
INTRODUCTION
Breastfeeding has well-defined benefits, for both the
mother and the baby, in addition to creating a moment of
affective relationship, it is rich food that protects the child
from infections, decreased risks of diabetes, obesity,
hypertension, and consequently helps in the development
of the face and speech, and opting to stop breastfeeding
should only be discouraged if there is any evidence of
drugs ingested by the mother and present in the milk and
does not have information about the drugs (Ministério da
Saúde, 2010).
Although breastfeeding is of great importance, there
are cases in which professionals must make exceptions
and investigate the benefits and harms of the
combination of medicines during lactation (Bedran,
1988).
The consumption of medication during pregnancy can
become a common practice, as well as concern whether
such drugs are excreted in breast milk, and if the
breastfeeding mother’s need to interrupt breastfeeding
(Bedran, 1988).
Most drugs are compatible with the lactation period,
even though they are eliminated in the milk, and
generally their concentration does not exceed 1 to 2% of
the dose ingested by the mother (Chaves, 2007).
The amount of medicines present in milk depends on
several factors, among them, the volume and concent-