Abstract In this case, a male Terrier dog, 14-year-old evaluated with a history of cardiac arrhythmias, coughing, rhinorrhagia and exercise intolerance for six mounths. The dog was died upon worsening of clinical signs. At necropsy, two masses of various sizes were observed in the heart-base region. Microscopically, cells from masses were atypic and polyhedral with eosinophilic-granular cytoplasm and basophilic nucleus with round to oval shape. The neoplastic cells were divided into lobules by connective tissue forming nests. In addition to these fndings, metastasis to the left kidney was observed. Immunohistochemically, the tumor cells from both primary and metastatic tissues showed immunoreactivity to monoclonal mouse anti-neuron specifc enolase antibody but were negative for cytokeratin, vimentin, chromogranin A, α smooth muscle actin and S-100. Based on the clinical, histological and immunohistochemical fndings, malignant aortic body tumor with left kidney metastasis was diagnosed in the present case. Keywords: Aortic body tumor, Dog, Immunohistochemistry Bir Köpekte Böbrek Metastazlı Aortik Body Hücre Tümörü Özet Bu olguda 6 aydır devam eden egzersiz intoleransı, öksürük, burun akıntısı ve kardiak aritmi şikayeti olan ve klinik bulguların kötüye gitmesi sonucunda ölen 14 yaşında erkek terrier ırkı köpek değerlendirildi. Nekropside kalp bölgesinde iki kitleye rastlandı. Mikroskobik olarak bakıldığında kitlelerden alınan kesitlerdeki hücrelerin atipi gösterdiği ve ovalden yuvarlağa kadar değişen bazoflik çekirdekli, eozinoflik-granüler sitoplazmalı ve polyhedral şekilli olduğu tespit edildi. Tümoral hücrelerin etrafı sıkı bağdokuyla çevrilmişti. Bu bulgulara ilaveten sol böbrekte tümör metastazına rastlandı. İmmunohistokimyasal olarak hem primer tümör kitlesi hem de metastazlı böbrekteki neoplastik hücreler monoklonal fare anti-neuron spesifk enolaz antikoru ile pozitif reaksiyon verirken, sitokeratin, vimentin, kromagranin A, α düz kas aktin ve S-100 antikorları ile yapılan boyamalar negatifdi. Sunulan bu vaka klinik, histopatolojik ve immunohistokimyasal sonuçları ile malign aortik body tümör olarak teşhis edildi. Anahtar sözcükler: Aortik body tümör, Köpek, Immunohistokimya Aortic Body Cell Tumor with Kidney Metastasis in a Dog [1] Mehmet Önder KARAYİĞİT 1  Öznur ASLAN 2 Latife ÇAKIR BAYRAM 1 Duygu YAMAN 1 Ayhan DÜZLER ³ İlknur KARACA BEKDİK 2 Görkem EKEBAŞ 1 [1] 1 2 3 Presented at VII. Veterinary Pathology Congress 08 th -10 th September 2014, Kars - TURKEY University of Erciyes, Faculty of Veterinary Medicine, Department of Pathology, TR-38039 Melikgazi, Kayseri - TURKEY University of Erciyes, Faculty of Veterinary Medicine, Department of Internal Medicine, TR-38039 Melikgazi, Kayseri - TURKEY University of Erciyes, Faculty of Veterinary Medicine, Department of Anatomy, TR-38039 Melikgazi, Kayseri - TURKEY INTRODUCTION Chemodectoma is a tumor arising from chemoreceptor cells which regulate level of blood pH, carbon dioxide and oxygen. Chemodectoma represents both aortic body tumors and carotid body tumors [1] . An aortic body tumor is localized in the tunica adventitia of the aortic arch whereas a carotid body tumor is arised in the carotid artery. The tumors in dogs are mostly benign but rarely malign and metastases to spleen, liver, bone, lung and myocardium [2-5] . Immunohistochemically, aortic body tumor cells usually stain for anti-neuron specific enolase (NSE), chromogranin A and S-100 [6-11] antibodies. To the best our knowledge, a case of metastatic-aortic body has not been reported in veterinary literature in Turkey. The aim of this case is to evaluate diagnostic implications for this important neo- plastic condition in dogs. CASE HISTORY A male Terrier dog, 14-year-old, was submitted with a history cardiac arrhythmias, coughing, rhinorrhagia and  İletşim (Correspondence)  +90 505 8180295  karayigit09@hotmail.com KafKas Universitesi veteriner faKUltesi Dergisi JoUrnal Home-Page: http://vetdergi.kafkas.edu.tr online sUbmission: http://vetdergikafkas.org Case Report Kafkas Univ Vet Fak Derg 21 (5): 785-788, 2015 DOI: 10.9775/kvfd.2015.13506 KVFD-2015-13506 Received: 02.04.2015 Accepted: 02.06.2015 Published Online: 03.06.2015