How to Cite: Khachian, A., Seyedoshohadaei, M., & Mousa, R. K. (2022). Investigating medication adherence and illness perception among patients with hypertension in Al-Nasiriyah Teaching Hospital in 2022. International Journal of Health Sciences, 6(S4), 6299–6309. https://doi.org/10.53730/ijhs.v6nS4.11158 International Journal of Health Sciences ISSN 2550-6978 E-ISSN 2550-696X © 2022. Manuscript submitted: 27 April 2022, Manuscript revised: 9 June 2022, Accepted for publication: 18 July 2022 1 Investigating medication adherence and illness perception among patients with hypertension in Al-Nasiriyah Teaching Hospital in 2022 Alice Khachian Department of Medical-Surgical, Nursing care research center, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran Mahnaz Seyedoshohadaei Department of Medical-Surgical Nursing, School of Nursing and midwifery, Iran University of Medical Science, Tehran, Iran Rushd Khudhur Mousa Department of Medical-Surgical, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran Corresponding author email: rushdnursing@gmail.com Abstract---Hypertension is one of the most common worldwide health problems, medication adherence is a major public health concern and leads to considerable morbidity, mortality, and healthcare costs. Hence, it is considering a serious challenge for the patients as well as for caregivers. The main objective of this study was to an Investigating Medication Adherence and Illness Perception Among Patients with Hypertension in Al-Nasiriyah Teaching Hospital. A quantitative descriptive cross-sectional design was performed among 424 adult hypertensive patients attending hypertension clinics in Al-Nasiriyah Teaching Hospital in Al-Nasiriyah, southern Iraq. The data were collected over a period of three months from April 6 th , 2022, to July 1 st , 2022, by using a questionnaire includes three parts, related to Socio- Demographic and clinical data, eight item-Morisky Medication Adherence Scale (8-MMAS), and Brief illness perception questionnaire (BIPQ). Data was analysis by using SPSS version 25, descriptive statistics (percentage, frequency, SD, mean) used to describe socio- demographic data, Inferential statistics (chi- square test) was used to assess the association between illness perception and treatment adherence, and Anova used to find the relationship between overall evaluation of (BIPQ), eight item 8-MMAS and Demographical data. Were the results revealed a total score of (BIPQ) were (Moderate) and the eight item-MMAS total score were (low adherences). There is a correlation between the (BIPQ) and the eight item-MMAS, the level of