_____________________________________________________________________________________________________ *Corresponding author: E-mail: vikasjjha7@gmail.com; Chemical Science International Journal 31(2): 1-14, 2022; Article no.CSIJ.88917 ISSN: 2456-706X (Past name: American Chemical Science Journal, Past ISSN: 2249-0205) Chemical Composition, Bioactive Potential, and Thermal Behaviour of Cyperus scariosus Essential Oil Vikas Jha a* , Reetikesh Patel a , Sakshi Devkar a , Mohd Aslam Shaikh b , Diksha Rai c , Shraddha Walunj c , Joshua Koli a , Tisha Jain b , Namrata Jadhav d , Shruti Narvekar a and Rushiraj Shinde b a National Facility for Biopharmaceuticals, G. N. Khalsa College, Mumbai, Maharashtra, India. b Department of Five Years Integrated Course in Bioanalytical Sciences, GNIRD, G.N. Khalsa College, Matunga-19, Mumbai, Maharashtra, India. c Department of Biotechnology, The Institute of Science, Mumbai, Maharashtra, India. d Department of Biotechnology, Elphinstone College, Mumbai, Maharashtra, India. Authors’ contributions This work was carried out in collaboration among all authors. Conception and design of study was done by authors VJ, DR, SW, NJ and MAS. Acquisition of data was by authors RP, SD, JK, and TJ. Analysis and interpretation of data was by authors VJ, DR, TJ and SW. Drafting the manuscript was by authors RS, SN, TJ, MAS and NJ. Revising the manuscript critically for important intellectual content was by authors SN, MAS, TJ, VJ and NJ. All authors read and approved the final manuscript. Article Information DOI: 10.9734/CSJI/2022/v31i230276 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/88917 Received 15 April 2022 Accepted 23 June 2022 Published 30 June 2022 ABSTRACT Plant derived oils have recently been found to be more effective in pharmaceutical sectors than synthetic goods since these plants contain physiologically active chemicals with a wide range of therapeutic effects. Essential oil, also known as essence, volatile oil, etheric oil, or aetheroleum, is a complex mixture of volatile elements biosynthesised by living organisms, which is particularly abundant in aromatic plants. This research summarizes facts on the chemistry of essential oil isolated from Cyperus scariosus on the one hand and their most important biological activities on the other. The essential oil components were determined to be a complex mixture of volatile chemicals such as monoterpenes, sesquiterpene hydrocarbons, and their oxygenated derivatives Original Research Article