Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/ijgo.12871 This article is protected by copyright. All rights reserved. REVIEW ARTICLE Guidelines for the management of the social and ethical challenges in brain death during pregnancy Anto Čartolovni 1,2 *, Dubravko Habek 1,3 1 Catholic University of Croatia, Zagreb, Croatia 2 Faculty of Health Sciences, University of Hull, Hull, UK 3 Department of Obstetrics and Gynecology, Clinical Hospital “Sveti Duh”, Zagreb, Croatia * Corresponding author: Anto Čartolovni, Catholic University of Croatia, Ilica 242, 10000 Zagreb, Croatia Email: anto.cartolovni@unicath.hr; a.cartolovni@hull.ac.uk Synopsis: The increasing number of live infants born to women sustaining prenatal brain death indicates an ethical duty to continue prolonged corporeal support despite lack of legal guidance. Keywords: Bioethics; Brain death; Clinical ethics; Corporeal support; Decision making; Human rights; Post-mortem delivery; Pregnancy