GYNAECOLOGY Endometrial Polyp Size and the Risk of Malignancy in Asymptomatic Postmenopausal Women Ahmet Namazov, MD; 1, * Ofer Gemer, MD; 1 Alon Ben-Arie, MD; 2 Osnat Israeli, MD; 3 Oshrit Bart, MD; 2 Oshra Saphier, MD; 4 Neta Mahler, MD; 2 Viki Kapustian, MD; 1 Tali Silberstein, MD 3 1 Department of Obstetrics and Gynecology, Barzilai University Medical Center, Faculty of Health Sciences, Ben-Gurion University of Negev, Ashkelon, Israel 2 Department of Obstetrics and Gynecology, Kaplan Medical Center, Faculty of Health Sciences, Hebrew University, Rehovot, Israel 3 Department of Obstetrics and Gynecology, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of Negev, Beer-Sheva, Israel 4 Department of Chemical Engineering, Sami Shamoon College of Engineering, Beer-Sheva, Israel Abstract Objective: The appropriate management of endometrial polyps in asymptomatic postmenopausal patients remains controversial. The aim of the study was to evaluate the relationship between endometrial polyp size and malignancy risk among asymptomatic postmenopausal women. Methods: This observational retrospective study investigated 472 postmenopausal asymptomatic women who underwent hysteroscopic polypectomy between 2010 and 2014 (Canadian Task Force Classification II-3). Results: Of the 472 women, premalignant and malignant lesions were found in 11 (2.33%) cases; four (0.84%) had endometrial carcinoma, and seven (1.49%) had atypical endometrial hyperplasia. The incidence of premalignant or malignant lesions among various cut-offs of polyp size (10, 15, 20 mm) was not significantly different. Conclusion: In the current series no significant risk factor for malignancy was found among different cut-offs of polyp size. Résumé Objectif : La prise en charge appropri ee des polypes endom etriaux chez les patientes m enopaus ees asymptomatiques demeure controvers ee. Le but de cette  etude  etait d’  evaluer la relation entre la taille des polypes endom etriaux et leur risque de malignit e chez les femmes m enopaus ees asymptomatiques. Méthodologie : Cette  etude r etrospective observationnelle portait sur 472 femmes m enopaus ees asymptomatiques qui ont subi une polypectomie hyst eroscopique entre 2010 et 2014 (classification II-3 du Groupe d’ etude canadien). Résultats : Parmi les 472 femmes, 11 (2,33 %) pr esentaient des l esions pr ecanc ereuses et malignes; 4 (0,84 %), un carcinome de l’endom etre, et 7 (1,49 %), une hyperplasie endom etriale atypique. L’incidence de l esions pr ecanc ereuses et malignes ne variait pas significativement entre les diff erents seuils de taille des polypes (10, 15 et 20 mm). Conclusions : Dans la s erie actuelle, aucun facteur de risque de malignit e significatif n’a  et e associ e aux diff erents seuils de taille de polypes. © 2018 Society of Obstetricians and Gynaecologists of Canada/LaSoci et e des obst etriciens et gyn ecologues du Canada. Published by Elsevier Inc. All rights reserved. J Obstet Gynaecol Can 2018;000(000):1-4 https://doi.org/10.1016/j.jogc.2018.07.019 INTRODUCTION E ndometrial polyps are localized endometrial over- growths consisting of endometrial stroma, glands, and blood vessels. 1 The prevalence of endometrial polyps is reported to be between 7.8% and 34.9%, depending on the population studied. 2 Although most endometrial polyps are Ahmet Namazov Key Words: Endometrial polyp, asymptomatic, postmenopausal, malignancy Corresponding author: Dr. Ahmet Namazov, Obstetrics- Gynecology Department, Barzilai Medical Center, Ashkelon, Israel. enamazov@gmail.com Competing interests: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for- profit sectors. Received on June 21, 2018 Accepted on July 30, 2018 000 JOGC 000 2018  1