Research Article Acceptability and Feasibility of Integrating Point-of-Care Diagnostic Testing of Sexually Transmitted Infections into a South African Antenatal Care Program for HIV-Infected Pregnant Women E. Morikawa , 1 M. Mudau, 2 D. Olivier, 2 L. de Vos, 2 D. Joseph Davey, 3,4 C. Price, 1 J. A. McIntyre, 5,6 R. P. Peters, 5,7,8 J. D. Klausner , 1,3 and A. Medina-Marino 2 1 Division of Infectious Disease, David Gefen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA 2 Research Unit, Foundation for Professional Development, Pretoria, South Africa 3 Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, USA 4 Department of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa 5 Anova Health Institute, Johannesburg, South Africa 6 School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa 7 Department of Medical Microbiology, School of Public Health and Primary Care, Maastricht University, Maastricht, Netherlands 8 Department of Medical Microbiology, University of Pretoria, Pretoria, South Africa Correspondence should be addressed to E. Morikawa; emorikawa@mednet.ucla.edu Received 23 October 2017; Revised 10 March 2018; Accepted 29 March 2018; Published 9 May 2018 Academic Editor: Bryan Larsen Copyright © 2018 E. Morikawa et al. Tis is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) infections may increase the risk of vertical transmission of the human immunodefciency virus (HIV). In resource-limited settings, symptomatic screening, and syndromic management of sexually transmitted infections (STIs) during pregnancy continue to be the standard of care. In the absence of diagnostic testing, asymptomatic infections in pregnant women go untreated. Objective. To describe the acceptability and feasibility of integrating diagnostic STI screening into frst antenatal care visits for HIV-infected pregnant women. Methods. HIV-infected pregnant women were recruited during their frst antenatal care visit from three antenatal care clinics in Tshwane District, South Africa, between June 2016 and October 2017. Self-collected vaginal swabs were used to screen for CT, NG, and TV with a diagnostic point-of-care (POC) nucleic acid amplifcation test. Tose with STIs were provided treatment per South African national guidelines. Results. Of 442 eligible women, 430 (97.3%) agreed to participate and were tested. Of those with a positive STI test result ( = 173; 40.2%), 159 (91.9%) received same-day results and treatment; 100% of STI-infected women were treated within seven days. Conclusions. Integration of POC diagnostic STI screening into frst-visit antenatal care services was feasible and highly acceptable for HIV-infected pregnant women. 1. Background Te high global prevalence of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) continues to impart adverse health outcomes in women. Dur- ing pregnancy, those infections may result in substantial fetal and neonatal morbidity and mortality [1–6]. Recent research further suggests that, among HIV-infected pregnant women, STIs may increase the risk of mother-to-child transmission (MTCT) of HIV via increased HIV viral load shedding resulting from genital infammation [7–9]. While some countries recommend universal diagnostic testing for STIs as a component of antenatal care [10], the World Health Organization (WHO) recommends symp- tomatic screening with syndromic management for STIs in resource-limited settings [1, 10, 11]. However, given that Hindawi Infectious Diseases in Obstetrics and Gynecology Volume 2018, Article ID 3946862, 6 pages https://doi.org/10.1155/2018/3946862