Case Report
A Rare Case of Pheohyphomycotic Lumbar Spondylodiscitis
Mistreated as Koch’s Spine
Shakti A. Goel,
1
Hitesh N. Modi,
1
Yatin J. Desai,
1
and Harshal P. Thaker
2
1
Department of Orthopaedics and Spine Surgery, Zydus Hospitals and Healthcare Research Pvt. Ltd., Taltej,
Ahmedabad, Gujarat, India
2
Dr. Harshal Taker’s Clinic, Ambawadi, Ahmedabad, Gujarat, India
Correspondence should be addressed to Hitesh N. Modi; modispine@yahoo.co.in
Received 7 November 2016; Revised 17 November 2016; Accepted 29 November 2016
Academic Editor: Mark K. Lyons
Copyright © 2016 Shakti A. Goel et al. Tis is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Pheohyphomycosis is an uncommon infection and its association in spondylodiscitis has not yet been reported. Te purpose of
this case report is to describe a rare case of Pheohyphomycotic spondylodiscitis and methods to diagnose and manage the patient
with less invasive techniques. A 29-year-old male patient presented to the outpatient department with complaints of gradually
increasing low back pain with bilateral lower limbs radicular pain since one and a half years. He had associated fever, weight loss,
voice changes, and dry, scaly, erythematous skin with elevated ESR. Te patient had been taking anti-Koch’s therapy since 1 year with
little relief in pain and no radiological improvement. Percutaneous pedicle biopsy of L4 vertebra was taken under local anaesthesia
and confrmed Pheohyphomycosis which was treated with antifungal medications. Te patient showed sequential improvement
with long term antifungal treatment. He was eventually able to walk independently without support.
1. Introduction
Pheohyphomycosis represents infections caused by pig-
mented flamentous fungi which contain melanin in their cell
walls [1]. Teir morphologic characteristics include hyphae,
yeast-like cells, or combination [2]. Tey are either associated
with Alternaria or Exophiala jeanselmei [3, 4].
Pheohyphomycosis is an uncommon infection and al-
most all reported cases have occurred in immunosuppressed
patients with 80 percent mortality rate [5]. Te disease is
transmissible through air, wind, and water. Te contacted
individuals and population can be easily afected by it and
usually it is too late to be successfully treated by the time the
disease is recognized. Whenever seen, these organisms afect
the skin and subcutaneous tissue with nodules or cyst [6].
Eye infections and plaques and granulomatous damage on the
body have also been reported [7]. However, efect on spine by
this organism in Southern Asia has not yet been seen.
Here we report a unique case of Pheohyphomycosis of
lumbosacral spine, previously mistaken for Koch’s spine (TB)
and treated accordingly. Te patient did not report any
improvement for a long time until the pedicle biopsy was
taken and antifungal treatment started.
Tuberculosis (TB) has been described as an ancient infec-
tious disease with evidence being discovered in centuries-
old skeletal remains [8]. Moreover, it is the most common
cause of spinal infection in south Asian population [9].
In recent decades, there has been a signifcant resurgence
of TB (Tuberculosis), causing 2-3 million deaths annually
worldwide [10, 11].
Due to the frequent prevalence of TB in spine, it is a
common practice to consider Koch’s spine (TB) as the frst
diferential in all spinal infections in developing nations.
Many of these patients get better with anti-Koch’s therapy
without the surgery [12]. Hence it is a common practice to
start anti-Koch’s therapy in patients while the biopsy report
is awaited [12]. However, rarely, other organisms besides TB
could be a reason for such an infection [13]. Tis is the frst
case report of Pheohyphomycosis causing spinal infection in
an immunocompetent host.
2. Case Report
A 29-year-old immunocompetent male patient presented
to the outpatient department with complaints of gradually
increasing low back pain since one and a half years. Te pain
Hindawi Publishing Corporation
Case Reports in Orthopedics
Volume 2016, Article ID 8705204, 5 pages
http://dx.doi.org/10.1155/2016/8705204