Advances in Psychology 心理学进展, 2017, 7(12), 1419-1429 Published Online December 2017 in Hans. http://www.hanspub.org/journal/ap https://doi.org/10.12677/ap.2017.712175 文章引用: 徐晓晓, 蒋(2017). 自闭症谱系障碍患者异常的大尺度脑研究. 心理学进展, 7(12), 1419-1429. DOI: 10.12677/ap.2017.712175 Atypical Large Scale Brain Network in Autism Spectrum Disorders Xiaoxiao Xu, Jun Jiang * Department of Basic Psychology, School of Psychology, Army Medical University (Third Military Medical University), Chongqing Received: Nov. 29 th , 2017; accepted: Dec. 15 th , 2017; published: Dec. 22 nd , 2017 Abstract Autism spectrum disorders (ASD) is a neurodevelopmental disorder involving abnormal activa- tion or functional connectivity of multiple brain regions. Compared with typically developing par- ticipants, autistic people show activation deficiencies within default mode network (DMN), execu- tive control network (ECN), salience network (SN) and mirror neuron system (MNS), and un- der-connectivity or over-connectivity within and between networks. In addition, these abnormal large scale brain networks are influenced by many factors, such as atypical brain structures, task state, participants’ age, and analysis methods. Future research needs to deepen the understanding of potential mechanisms under autism brain connectivity, explore sensitive brain intervention methods for ASD and promote the early identification, diagnosis and treatment of ASD. Keywords Autism Spectrum Disorders, Large Scale Brain Network, fMRI 自闭症谱系障碍患者异常的大尺度脑网络研究 徐晓晓，蒋 军 * 陆医大学(第三医大学)心理学院基础心理学教研室，重庆 收稿日期：2017年11月29日；录用日期：2017年12月15日；发布日期：2017年12月22日 摘 要 自闭症谱系障碍(Autism spectrum disorders, ASD)是一种涉及多个大脑区域激活或能连接异常的神 * 通讯作者。