DOI: 10.21276/aimdr.2018.4.4.OT1 Original Article ISSN (O):2395-2822; ISSN (P):2395-2814 Annals of International Medical and Dental Research, Vol (4), Issue (4) Page 1 Section: Ophthalmology Study Of The Surgical Outcome Of Sutureless Glueless Conjunctival Autograft In Pterygium Excision Surgery. Roopam Chauhan 1 , Jaya Devendra 2 , P.S. Rastogi 3 , Ashish Chander 4 , Gopesh Mehrotra 5 1 Junior Resident, Department of Ophthalmology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India. 2 Professor and Head, Department of Ophthalmology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India. 3 Assistant Professor, Department of Ophthalmology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India. 4 Associate Professor, Department of Ophthalmology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India. 5 Assistant Professor, Department of Ophthalmology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India. Received: May 2018 Accepted: June 2018 Copyright: © the author(s), publisher. Annals of International Medical and Dental Research (AIMDR) is an Official Publication of “Society for Health Care & Research Development”. It is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non- commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT Background: Pterygium is a hyperplastic elastoid wing shaped degenerative condition of the subconjunctival tissue which proliferates as vascularized granulation tissue infiltrating the cornea destroying the superficial layers of stroma and Bowman’s membrane causing corneal distortion and significant amount of astigmatism. Conjunctival autograft is a relatively new and effective surgical technique with good aesthetic results in the management of primary pterygium. Objective: To evaluate the surgical outcome in terms of recurrence and other complications of sutureless glueless conjunctival autograft in pterygium excision. Setting: Department of Ophthalmology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh. Methods: Prospective interventional non randomized hospital based case series was carried out in 50 eyes with primary pterygium. Pterygium excision with limbal conjunctival autograft without glue or suture was performed in all patients. The patients were followed post operatively on day 1, day 7, 1 month and 6 months. Recurrence and other complications were noted at each visit. Results: Mean age of the study population was 36.96 11.39 years, 64% were males with maximum patients (72%) presenting in the age group of 20-40 years. The overall complication rate was 10%. Graft retraction was seen in 4%, Conjunctival Cyst in 2% and 1 case showed Graft Rejection. Recurrence rate was noted to be 2% at the end of 6 months. Conclusion: Sutureless glueless conjunctival autograft following pterygium excision is a simple, safe and economical procedure for the treatment of pterygium having excellent outcome. Keywords: Pterygium, sutureless, glueless conjunctival autograft, recurrence. INTRODUCTION The term ‘pterygium’ has its origin from the ancient Greek word (pteryx) = wing and (gion) = fin. Therefore, pterygium is described as a triangular ‘wing-like’ growth consisting of conjunctival epithelium and hypertrophied subconjunctival connective tissue that occurs nasally or temporally in the interpalpebral fissure, encroaching onto the cornea. [1] The worldwide prevalence rates vary between 0.3- 2.9%, [2,3] higher in the ‘Pterygium Belt’ having geographical latitudes of 40° north and south of the equator, [1] the peri-equatorial region which includes India. The UV Type B light in solar radiation has been implicated as a major environmental risk factor in Name & Address of Corresponding Author Dr. Ashish Chander Associate Professor, Department of Ophthalmology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India. the pathogenesis of pterygium. [2,3] Hence, men with outdoor work are affected more commonly than women. [4] Pterygium is a hyperplastic, elastoid wing shaped degenerative condition of the sub-conjunctival tissue which proliferates as vascularized granulation tissue to infiltrate the cornea destroying the superficial layers of stroma and bowman’s membrane. [5,6] Molecular genetic alterations like loss of heterozygosity, point mutations of proto-oncogenes such as k-ras and alterations in the expression of tumour suppressor genes such as p53 or p63 have pointed towards pterygium being a proliferative rather than a degenerative condition. [7] The tractional force of contractile elements within the pterygium lead to mechanical distortion and flattening of the cornea in its horizontal meridian resulting in hypermetropic with the rule astigmatism. [8,9] The indications for pterygium surgery are: (a) Visual Impairment (b) Recurrent Inflammation (c) Motility Restriction (d) Cosmetic Disfigurement.