22 Surg Cosmet Dermatol 2016;8(1):22-7. Comparative study: Hands rejuvenation treatment using intense pulsed light isolatedly or associated with 1,340nm non- ablative fractional laser Estudo comparativo: tratamento do rejuvenescimento de mãos utilizando a luz intensa pulsada isolada ou associada ao laser fracionado não ablativo 1340nm http://dx.doi.org/10.5935/scd1984-8773.20168102 ABSTRACT Introduction: The dorsum of the hands is a visible part of the body and needs special attention regarding rejuvenation treatments. The combination of different techniques in this area is important to increase the effectiveness of the treatments. Objective: This study was aimed to evaluate the clinical efficacy of a fractional non-abla- tive laser (1,340nm Nd:YAP) combined with intense pulsed light (IPL) for rejuvenating the hands. Methods:A prospective comparative study evaluated 11 patients complaining of aging on hands, for 90 days. Two sessions were carried out with a two-week interval using IPL and 1,340nm Nd:YAP laser. The left hand was treated with 1,340nm Nd:YAP laser associated with IPL and the right hand with isolated IPL. The improvement was rated using scores from 1 to 4, evaluating the parameters: wrinkles, pigmentation, brightness, keratosis and overall rejuvenation observing the elasticity and filling of visible structures such as bones, tendons and vessels. Results: By analyzing the frequencies of the categories of the variables, it was possible to ob- serve that there was a higher frequency of improvement in the left hand. For the comparative analysis of the studied variables, the mean value of each variable computed for each hand, evidenciated that the variable overall rejuvenation and the left hand showed more marked improvements for the studied characteristics.Ten among 11 patients had a higher satisfaction degree with the combined treatment, with absence of significant adverse effects. Conclusion:The association of 1,340nm laser to the IPL was shown to be safe and more effective than isolated intense pulsed light in the rejuvenation of the hands. Keywords: lasers; rejuvenation; hand ABSTRACT Introduction: The dorsum of the hands is a visible part of the body and needs special attention regarding rejuvenation treatments.The combination of different techniques in this area is important to increase the effectiveness of the treatments. Objective: This study was aimed to evaluate the clinical efficacy of a fractional non-ablative laser (1,340nm Nd:YAP) combined with intense pulsed light (IPL) for rejuvenating the hands. Methods: A prospective comparative study evaluated 11 patients complaining of aging on hands, for 90 days.Two sessions were carried out with a two-week interval using IPL and 1,340nm Nd:YAP laser. The left hand was treated with 1,340nm Nd:YAP laser associated with IPL and the right hand with isolated IPL. The improvement was rated using scores from 1 to 4, evaluating the parameters:wrinkles, pigmentation, brightness, keratosis and overall rejuvenation observing the elasticity and filling of visible structures such as bones, tendons and vessels. Results: By analyzing the frequencies of the categories of the variables, it was possible to observe that there was a higher frequency of improvement in the left hand. For the comparative analysis of the studied variables, the mean value of each variable computed for each hand, evidenciated that the variable overall rejuvenation and the left hand showed more marked improvements for the studied characteristics. Ten among 11 patients had a higher satisfaction degree with the combined treatment, with absence of significant adverse effects. Conclusion: The association of 1,340nm laser to the IPL was shown to be safe and more effective than isolated intense pulsed light in the rejuvenation of the hands. Keywords: lasers; rejuvenation; hand Original Articles Author: Valeria Campos 1 Luciana Maluf 2 Luz Marina Hannah Grohs 3 Stela Cignachi 4 Mariana Isis Wancizinski 5 Juliana Fávaro Izidoro 5 Fabiola Schauffler Stock 6 Marcella Ledo Martins Costa 7 1 Visiting Instructor, Faculdade de Medicina de Jundiaí - Jundiaí (SP), Brazil and Faculda- de de Medicina de Mogi das Cruzes - Mogi das Cruzes (SP), Brazil. 2 Preceptor, Laser Clinic, Faculdade de Medi- cina do ABC (FMABC) - Santo André (SP), Brazil 3 Dermatologist physician - Curitiba (PR), Brazil. 4 Dermatologist physician - Caxias do Sul (RS), Brazil 5 Dermatologist physician - São Paulo (SP), Brazil 6 Dermatologist physician – São Bonifácio (SC), Brazil. 7 Collaborating Instructor of Dermatologic Surgery, Faculdade de Medicina de Jundiaí - Jundiaí (SP), Brazil Correspondence: Valéria Campos Av. Nove de Julho, 1717 13208-056 – Jundiaí – SP E-mail: stelacig@gmail.com Received on: 10/01/2016 Approved on: 20/03/2016 This study was performed at the Faculdade de Medicina de Jundiaí - Jundiaí (SP), Brazil. Financial support: None Conflict of interests: None