Review Chemodosimeters for optical detection of fluoride anion Sukhvinder Dhiman a , Manzoor Ahmad a , Nancy Singla a , Gulshan Kumar b , Prabhpreet Singh a,⇑ , Vijay Luxami b,⇑ , Navneet Kaur c , Subodh Kumar a,⇑ a Department of Chemistry, Center for Advanced Studies, Guru Nanak Dev University, Amritsar143005, Punjab, India b School of Chemistry and Biochemistry, Thapar Institute of Engineering and Technology, Patiala, Punjab, India c Department of Chemistry, Center for Advanced Studies, Panjab University, Chandigarh, India article info Article history: Received 3 September 2019 Accepted 21 November 2019 abstract Chemodosimeters – the reaction based sensing systems for F  ions provide the significantly higher selec- tivity due to specificity of their reactions and also better opportunities for analysis in aqueous environ- ment as these are independent of hydrogen bonding interactions in comparison to those of chemosensors. In the present review, the literature appeared between years 2012–2018 has been com- prehensively presented for chemodosimeters based on the selective interactions of F  ion towards silicon, boron, phosphorous, antimony centers in variety of fluorophores. Also, the chemodosimeters undergoing displacement of an organic fluorophore or water molecule present on the metal center with that of F  ion or displacement of metal ion from the fluorophore resulting in optical changes have been discussed sep- arately. These fluorophores result in highly selective change in their optical (fluorescence, absorbance, chemiluminescence) behaviour only with F  ion and so the discussion on other anions has been limited to the cases where they significantly interfere in analysis of F  ion. During these discussions, the attention has been also given to the source of F  ion from inorganic salts (NaF/KF/CsF) or to organic salts like tetra (n-butyl)ammonium fluoride. The review covers 280 references. Ó 2019 Elsevier B.V. All rights reserved. Contents 1. Introduction ........................................................................................................... 2 2. Chemodometers based on silicon- F  ion interactions ......................................................................... 3 2.1. F  ion initiated silicon–oxygen bond cleavage .......................................................................... 3 2.1.1. Desilylation of phenoxy derivatives ........................................................................... 3 2.1.2. Desilylation associated with activation of ESIPT ................................................................ 18 2.1.3. Desilylation followed by quinone-methide as self-immolated group ................................................ 20 2.1.4. Desilylation followed by cyclization and other reactions ......................................................... 27 2.1.5. Desilylation associated with chemiluminescence ................................................................ 28 3. Chemodosimeters based on boron – F  ion interactions ....................................................................... 30 3.1. Triarylboron based chemodosimeters for F  ion ........................................................................ 30 https://doi.org/10.1016/j.ccr.2019.213138 0010-8545/Ó 2019 Elsevier B.V. All rights reserved. Abbreviations: BODIPY, boron-dipyrromethene; CDs, carbon dots; CTAB, cetyl trimethyl ammonium bromide; DMF, dimethyl formamide; DMSO, dimethyl sulfoxide; EET, excitation energy transfer; FE, fluorescence enhancement; FI, fluorescence intensity; FQ, fluorescence quenching; GO, graphene oxide; HEPES, 4-(2-hydroxyethyl)-1-piper azineethanesulfonic acid; ICT, internal charge transfer; LOD, limit of detection; MOF, metal organic framework; NBD, 7-nitro-2,1,3-benzoxadiazole; NPs, nanoparticles; PBS, phosphate buffer saline; PEG, polyethylene glycol; PET, photo-induced electron transfer; PMMA, poly (methyl methacrylate); QD, quantum dot; U, quantum yield; TBAF, tetra butyl ammonium fluoride; TBDMS, tert-butyl dimethyl silyl; TBDPS, tert-butyl diphenyl silyl; THF, tetrahydrofuran; TIPS, tri- isopropyl silyl; TMS, trimethyl silyl; TRIS, tris (hydroxymethyl)aminomethane; TP, two photon. ⇑ Corresponding authors. E-mail addresses: prabhpreet.chem@gndu.ac.in (P. Singh), vj_luxami@yahoo.co.in (V. Luxami), subodh.chem@gndu.ac.in (S. Kumar). Coordination Chemistry Reviews 405 (2020) 213138 Contents lists available at ScienceDirect Coordination Chemistry Reviews journal homepage: www.elsevier.com/locate/ccr