Leprostigma negatively impacts on leprosy afflicted persons (LAPs). Understanding the concept of Leprostigma is very important in providing optimal nursing care for LAPs. However, this concept remains obscure in the literature and has been defined differently in various studies. The use of different terms for this concept has made its use more complicated in practice. This concept analysis attempts to analyze the leprostigma concept to clarify, reduce ambiguities, semantic integration, and increase stability in applying the concept. The relevant literature was reviewed using Walker and Avant's framework, and the attributes of Leprostigma were determined. Leprostigma manifests in three main faces that their attributes determine the boundaries of the concept. Enacted-Leprostigma defines as externally humiliating behaviors and discrimination experienced and perceived by LAPs. Felt-Leprostigma is the anticipation, expectance, prejudgment, or fear of LAPs of label attachment and discrimination by others. Self-leprostigma defines as an unfavorable personal experience of self-discredited, feeling of inferiority, and self-loathing. Leprostigma developed from a primitive concept with emphasis on LAPs attributes to the concept with a complex social structure. It occurs in a broad spectrum of unfair and negative consequences through a dynamic process. This concept analysis can improve the implementation of more extended studies and the development of research tools as well as practice. It is observed that different kinds of Leprostigma have overlapping values and affect each other. As a result of analysis presented in this study, it is recommended that the term "Leprostigma" be used instead of various leprosy-related stigma terms. Concept Analysis, Leprostigma, Leprosy, Stigma, Walker and Avant. Keywords : http://www.ijl.org.in Review Article Indian J Lepr 2020, 92 : 243-256 © Hind Kusht Nivaran Sangh, New Delhi 1 2 3 4 SM Mahdavi Shahri, Ph.D. Student in Nursing, School of Nursing and Midwifery, International Campus, Iran University of Medical Sciences, Tehran, Iran. N Mohammadi, Associate Professor, Nursing Care Research Center, Iran University of Medical Sciences, Tehran, Iran. A Nikbakht Nasrabadi, Professor, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran. A Khamesipour, Professor, Center for Research and Training in Skin Disease and Leprosy, Tehran University of Medical Sciences, Tehran,Iran. SM Mahdavi Shahri, Correspondence : Email : mahdavi_m@razi.tums.ac.ir Leprostigma : A Concept Analysis SM Mahdavi Shahri , N Mohammadi , A Nikbakht Nasrabadi , A Khamesipour 1 2 3 4 Introduction Leprosy is one of the age-oldest diseases which had been described in the ancient literature of India and China . In scientific writings, perhaps (Grön 1973, Trautman 1984, Bennett et al 2008) the oldest narrative belongs to Avicenna, which described leprosy and patients characteristics (Zamparoni 2017). Leprosy remains a significant public health problem in several parts of the world. In 2017, WHO reports that there were Received : 23.01.2020 Accepted : 17.06.2020