Indo-Global Journal of Pharmaceutical Sciences, 2011, Vol 1., Issue 1: Page No. 85-98 85
Review & Future Perspectives of Using Vasicine, and Related
Compounds
Rachana
*
, Basu Sujata, Pant Mamta, Kumar Manoj Priyanka and Saluja Sonam
a
Department of Biotechnology, Jaypee Institute of Information Technology, Sec-62, Noida-201307 , U.P, India
Received: 16
th
Dec. 2010; Accepted: 09
th
Jan 2011
Address for Correspondance: rachana.dr@gmail.com
Abstract— Vasicine molecule was first isolated in 1924 and most of the work on this molecule was done between 1960s-
1980s. The plant Adhatoda vasica (Acanthaceae) is the main source of this molecule. This plant has been used in India for
2000 years for the treatment of respiratory ailments and for its abortifacient activities. It is surprising to note that, even if, it
has been used effectively and extensively in the above mentioned areas since ancient times till date, and a huge amount of
work has already been done on its derivative “Bromhexine”, very few recent reports are available for its molecular
mechanism of action. The present article is an attempt to compile the literature available for this molecule and to further
analyze its probable potential use in the above areas, including few more other areas as well. © 2011 IGJPS. All rights
reserved
Keywords : Vasicine, Peganine, Adhatoda vasica(Zeylanica), Asthama, Bisolvon, Bromhexine.
INDO GLOBAL
JOURNAL OF
PHARMACEUTICAL
SCIENCES