ARTIGO ORIGINAL DOI: https://doi.org/10.26694/repis.v7i0.10778 Adesão à Profilaxia Pré-Exposição ao HIV: como estamos no Brasil? Adherence to the Pre-Exposure Prophylaxis to the HIV: how are we doing it in Brazil? Adherencia a la profilaxis previa a la exposición al VIH: ¿cómo estamos en Brasil? Raíssa Lissoni de Andrade Nogueira 1 , Jéssica Fernanda Corrêa Cordeiro 2 , Lucas Lazarini Bim 2 , Euripedes Barsanulfo Gonçalves Gomide 3 , Denise de Andrade 2 , André Pereira dos Santos 2,3 Como citar este artigo: Nogueira RLA, Cordeiro JFC, Bim LL, Gomide EBG, Andrade D, Santos AP. Adherence to the Pre-Exposure Prophylaxis to the HIV: how are we doing it in Brazil?. Rev Pre Infec e Saúde [Internet]. 2021;7:10778. Available from: https://revistas.ufpi.br/index.php/nupcis/article/view/10778 DOI: https://doi.org/10.26694/repis.v7i0.10778 1 Escola de Enfermagem de Ribeirão Preto, Departamento de Enfermagem Fundamental, Ribeirão Preto, São Paulo, Brasil. 2 Escola de Enfermagem de Ribeirão Preto, Programa de Pós-Graduação em Enfermagem Fundamental, Ribeirão Preto, São Paulo, Brasil. 3 Escola de Enfermagem de Ribeirão Preto, Programa Interunidades de Doutoramento em Enfermagem, Ribeirão Preto, São Paulo, Brasil. ABSTRACT Introduction: The recent insertion of the Pre-Exposure Prophylaxis to the HIV as a strategy of controlling HIV infection in the Unified Health System, and the studies related to the thematic can enhance its effectiveness in the control of HIV infection. The study aims to analyze the current scenario of adherence to HIV Pre-Exposure Prophylaxis in Brazil and understand the barriers and facilitative aspects for effective adherence. Outline: This is an integrative literature review study, carried out in the main databases. The inclusion criteria applied were primary studies and published until September 2019. Results: It was observed high adherence to the Pre-Exposure Prophylaxis for the HIV. The barriers and facilitative aspects for adherence to HIV Pre-Exposure Prophylaxis are associated with social stigma, lack of knowledge about the efficacy and safety of prophylaxis and, especially, low awareness of sexual practices and high-risk behaviors for the HIV transmission. Implications: High adherence to HIV Pre-Exposure Prophylaxis was observed in the most vulnerable population segments. Barriers to adherence to HIV Pre-Exposure Prophylaxis can be overcome with greater investment in the dissemination of its benefits to the population. DESCRIPTORS Infection Control; HIV; Pre-Exposure Prophylaxis; Medication Adherence; Brazil. Autor correspondente: André Pereira dos Santos Address: R. Prof. Hélio Lourenço, 3900, Vila Monte Alegre CEP: 14040-902 – Ribeirão Preto, São Paulo, Brazil Telephone: +55 (16) 3315-4321 E-mail: andrepereira.educa@gmail.com Submetido: 2020-06-01 Aceito: 2021-02-25 Publicado: 2021-11-27 revistas.ufpi.br Rev Pre Infec e Saúde. 2021;7:10778 1