PSEUDOMONAL CHOROIDAL ABSCESS
AFTER ROUTINE PARS PLANA
VITRECTOMY IN AN
IMMUNOSUPPRESSED PATIENT
Kendrick M. Wang, BS, Tin Yan Alvin Liu, MD, Julia Sein, MD,
J. Fernando Arevalo, MD, PhD
Purpose: To describe an unusual case of pseudomonal choroidal abscess which
developed after a routine pars plana vitrectomy in an immunosuppressed patient.
Methods: Case report. A 61-year-old woman with a history of rheumatoid arthritis
and ulcerative colitis on abatacept underwent pars plana vitrectomy. A few days after
the patient’ s operation, a partially serous choroidal detachment was identi fied. Her
choroidal detachment increased in size despite prednisone therapy, and she was
taken to the operating room for repeat vitrectomy and choroidal drainage. Intra-
operatively, there was no signi ficant intraocular inflammation, but purulent whitish
material was expressed during external choroidal drainage which grew Pseudomonas
aeruginosa.
Results: The patient was given intravenous antibiotics. Systemic infectious workup
was negative for blood and urine cultures. The patient was transitioned to oral
antibiotics, but had persistent eye pain after discharge and vision remained at count
fingers. A computed tomography orbit scan with contrast showed persistent choroidal
abscess, and intravitreal ceftazidime injections were administered. The patient’s
subjective pain resolved within several days of the first intravitreal injection; repeat
ultrasound also showed interval resolution of the choroidal elevation. One year after the
resolution of her choroidal abscess, her visual acuity was Snellen 20/250 in the affected
eye.
Conclusion: Isolated choroidal bacterial abscess is a possible, but rare, complica-
tion of pars plana vitrectomy. Although visual prognosis is poor, especially for
pseudomonal choroidal abscesses, aggressive treatment with timely choroidal
drainage, systemic antibiotics, and intravitreal antibiotics may allow recovery of some
ambulatory vision.
RETINAL CASES & BRIEF REPORTS 00:1–5, 2019
From the Wilmer Eye Institute, Johns Hopkins
University School of Medicine, Baltimore, Maryland.
W
e report an unusual case of pseudomonal
choroidal abscess which developed after
a routine pars plana vitrectomy for symptomatic
vitreomacular traction in an immunosuppressed
patient. The clinical presentation, diagnostic workup,
and treatment outcomes will be discussed and com-
pared with other cases of choroidal abscesses in the
existing literature.
Case Report
A 61-year-old white woman presented to the retina clinic,
complaining of 6 months of decreased vision in her left eye. Her
medical history was significant for rheumatoid arthritis and ulcerative
colitis, for which she took subcutaneous abatacept once a week, an
immunomodulatory agent. She underwent cataract surgery in her left
eye 16 months before presentation, and she had no history of
intravenous (IV) drug use or recent dental procedures. The visual
acuity and examination were normal for her right eye. Her left eye
visual acuity measured Snellen 20/80, and optical coherence
tomography of the left eye macula revealed vitreomacular traction
at the fovea (Figure 1A), for which pars plana vitrectomy with lifting
of the posterior hyaloid was performed. The surgery was a standard
1
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