Predictive Factors for Participation in Colorectal Cancer Screening: A Systematic Review Shirin Barzanjeh Atri 1 , Mina Hosseinzadeh 2 , Mohamad Asghari Jafarabadi 3 , Mohammad Hasan Sahebihagh 4,5 , Leila Ebadi 6* 1 Faculty of Nursing and Midwifery, Community Health Nursing Department, Tabriz University of Medical Sciences, Tabriz, Iran 2 Nursing and Midwifery Faculty, Tabriz University of Medical Science, Tabriz, Iran 3 Road Traffic lnjury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran 4 Tabriz Health Services Management Research Center, Health Management and Safety Promotion Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran 5 Department of Community Health Nursing, Tabriz University of Medical Sciences, Tabriz, Iran 6 Community Health Nursing, Tabriz University of Medical Sciences, Tabriz, Iran ABSTRACT Background: Colorectal cancer (CRC) is one of the prevalent diseases that can be diagnosed timely using appropriate screening programs. This study aimed to review the predictive factors for participation in colorectal cancer screening. Methods: International databases including PubMed, ISI and Scopus were considered for search of English articles by 30 December, 2018. Thirty-one published articles were finally entered into the study. Keywords were “colorectal cancer”, “colorectal neoplasm”, “predictor”, “screening”, “Fecal Occult Blood Test (FOBT)”, “Fecal Immunochemical Test (FIT)”, “education”, “smoking”, “obesity” or a combination of them in the title/abstracts. Findings: There were 367,248 subjects reviewed in this systematic review of 31 published articles consisted of two cohorts, one quasi-experimental; one mixed method, three randomized trial and twenty-six cross-sectional design. Conclusion: According to the results, knowledge, income, being married and female, trust to physician and kindly contact of health providers, counselling centres disorders were the main predictive factors for participation in the CRC screening programs. Key words: Colorectal cancer, Colorectal neoplasm, Predictor, Screening, FOBT, FIT HOW TO CITE THIS ARTICLE: Shirin Barzanjeh Atri, Mina Hosseinzadeh, Mohamad Asghari Jafarabadi, Mohammad Hasan Sahebihagh, Leila Ebadi, Predictive factors for participation in colorectal cancer screening: A systematic review, J Res Med Dent Sci, 2019, 7(2): 109-115 Corresponding author: Leila Ebadi e-mail : ley.256@yahoo.com Received: 13/03/2019 Accepted: 25/03/2019 INTRODUCTION Cancer is one of the prevalent diseases that account for a large volume of lethal consequences as well as care efforts [1-5]. Among them, Colorectal Cancer (CRC) is now responsible for a large part of the burden of cancer and the fourth leading cause of cancer death worldwide [6]. The CRC is the second most common cancer in women [7,8] and after breast cancer is the most common cause of death in women [9,10]. Meanwhile, it can also be considered as the third most common cancer in men worldwide. It is estimated that the incidence and mortality rate of the CRC will increase by 77% and 80% by 2030, respectively [7]. The incidence and mortality rate of this cancer varies in different regions [11,12], which is more common in developing countries than in the rest of the world [13]. Fortunately, its mortality rate is declining in many western countries [7]. Cancer is also the third leading cause of death in Iran, so that the incidence of CRC has increased during the past 25 years in Iran especially among younger people [14,15]. Various risk factors have been reported for colorectal cancer, including aged more than 50 years, family history, nutrition patterns, obesity, inactivity, and cigarette smoking. However, the main cause of it has not been accurately known [9,16-19]. The survival rate of the CRC is reported 5 years after diagnosis [13], which is highly dependent on the time of diagnosis, so secondary prevention, which is the early Journal of Research in Medical and Dental Science 2019, Volume 7, Issue 2, Page No: 109-115 Copyright CC BY-NC 4.0 Available Online at: www.jrmds.in eISSN No.2347-2367: pISSN No.2347-2545 JRMDS J o u r n a l o f R e s e a r c h i n M e di ca l a n d D e n t a l S c i e n c e Journal of Research in Medical and Dental Science | Vol. 7 | Issue 2 | March 2019 109 ✉