Mal J Med Health Sci 16(3): 21-28, Sept 2020 21 Malaysian Journal of Medicine and Health Sciences (eISSN 2636-9346) ORIGINAL ARTICLE Assessment of Clinical, Risk Factors Profile and Clinical Pharmacist Care Services on Management and Prevention of Coronary Artery Disease Complications Among Diabetic Patients in a Tertiary Care Hospital Practice Abbavannagari Bharath Kumar 1 , Marakanam Srinivasan Umashankar 2 , Sandeep Poddar 3 1 Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur- 603203, Tamil Nadu, India. 2 Department of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur-603203, Tamil Nadu, India. 3 Senior Research Director, Lincoln University College, 47301 Petaling Jaya, Selangor, Malaysia ABSTRACT Introduction: Diabetes is a chronic metabolic disease and noted to be incidence is intensifying globally and contem- plated as epidemic. The study is aimed to assess the coronary artery disease risk profile associated diabetes mellitus patient and to identify the clinical pharmacist care services in the management and to control the risk burden in the clinical practice. Method: A prospective observational study was conducted among the consecutive patients of coronary artery disease associated diabetic patients in a tertiary care teaching hospital over 6 months period. A sam- ple of 150 patients was recruited in the study. Data analysis was done with graph pad prism software 5.01. Results: The present study revealed that coronary artery disease in diabetes was more prevalent in age group between 41-50 years. About 54.66% patients with hyperlipidemia were at risk to develop the coronary artery disease complication. Glycated hemoglobin test was detected in 40% of the patient showing abnormal levels and around 43.33% of patient had an abnormal fasting blood sugar level. The study showed only 32% of patients was prescribed Insulin & oral hy- poglycemic agents and 13 % were treated with statins. Conclusion: It could be concluded that the causative factors should be controlled and treated with an early need for amalgamation of clinical pharmacist care services with the health care team on life style modification counseling could ultimately improve the patient health outcomes and also lowers progression of coronary artery disease risk complications among diabetic patients. Keywords: Coronary artery disease, Diabetes mellitus, Hyperlipidemia, Clinical pharmacist, Care services. Corresponding Author: Marakanam Srinivasan Umashankar, PhD Email: umashankarms269@gmail.com Tel: +91 9840333269 INTRODUCTION Diabetes mellitus has a broad range of complications which includes macro vascular and micro vascular complications which lead to develop severe coronary artery diseases amongst the diabetes mellitus affected patients rather than non-diabetic patients. The release of inflammatory cells, proliferation of vascular smooth muscle cells led to endothelial dysfunction can cause the plaque instability and thrombus formation can lead to development of coronary artery disease. Diabetic patients can increase two to four folds of developing coronary artery disease risk. Cardiovascular diseases are creating primary health problem and causing mortality and morbidity in worldwide. Around 17.9 million people die from cardiovascular disease every year and accounts for 31% death globally (1-3). Recent statement from the International Diabetes Federation estimated that people around 387 million affected with diabetes mellitus in 2013 and which may to rise 592 million by 2035. The health care cost of diabetes mellitus is largely attributed to many complications such as hypertension, coronary artery disease, peripheral vascular disease, neuropathy, retinal problems and renal failure (4-5). Cardiovascular diseases consist of congestive heart failure, congenital heart disease, cardiomyopathy, cardiac arrhythmia, coronary heart disease, rheumatic heart disease, stroke, and peripheral arterial disease etc. The etiology of coronary artery disease is a complex process following a series of coronary artery disease development with severe risk factors. Coronary artery disease comprises an array of manifestations which extend from stable angina, unstable angina, ST-elevation myocardial infarction non-ST elevation myocardial