Accepted Manuscript Title: CHARACTERIZATION OF THREE MAIN DEGRADATION PRODUCTS FROM NOVEL ORAL ANTICOAGULANT RIVAROXABAN UNDER STRESS CONDITIONS BY UPLC-Q-TOF-MS/MS Author: Nathalie R. Wingert Nat´ alia O. dos Santos Matheus A.G. Nunes Patr´ ıcia Gomes Edson I. M ¨ uller ´ Erico M.M. Flores Martin Steppe PII: S0731-7085(16)30053-X DOI: http://dx.doi.org/doi:10.1016/j.jpba.2016.01.053 Reference: PBA 10479 To appear in: Journal of Pharmaceutical and Biomedical Analysis Received date: 10-6-2015 Revised date: 22-1-2016 Accepted date: 23-1-2016 Please cite this article as: Nathalie R.Wingert, Nat´ alia O.dos Santos, Matheus A.G.Nunes, Patr ´ icia Gomes, Edson I.M¨ uller, ´ Erico M.M.Flores, Martin Steppe, CHARACTERIZATION OF THREE MAIN DEGRADATION PRODUCTS FROM NOVEL ORAL ANTICOAGULANT RIVAROXABAN UNDER STRESS CONDITIONS BY UPLC-Q-TOF-MS/MS, Journal of Pharmaceutical and Biomedical Analysis http://dx.doi.org/10.1016/j.jpba.2016.01.053 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.