48 Turk J Hematol 2008; 25:48-50 First observation of homozygote Hb Q-Iran (alpha 75 (EF4) Asp-His) Hilal Özda¤ 1 , ‹nci Y›ld›z 2 , Nejat Akar 3 1 Biotechnology Institute of Ankara University, Ankara, Turkey 2 Cerrahpasa University, School of Medicine, ‹stanbul, Turkey 3 Pediatric Molecular Genetics Department of Ankara University, School of Medicine Ankara, Turkey ) akar@medicine.ankara.edu.tr ABSTRACT The first observation of homozygote Hb Q-Iran (α1 75(EF4) Asp-His) is presented in this report. The cli- nical and hematological data of the index case, his father and mother showed that homozygous or heterozygo- us Hb Q-Iran has no clinical importance. Key words: Hemoglobin, Q-Iran ÖZET Homozigot Hb Q ‹ran'›n (alpha 75 (EF4) ASP-HIS) ilk kez belirlenmesi Sivas kökenli anormal hemoglobini olan bir çocu¤a moleküler analizle Homozigot Hb Q-Iran (α1 75(EF4) Asp-His tan›s› konulmufltur. Anahtar kelimeler: Hemoglobin, Q-‹ran Received: 20.05.2007 • Accepted: 06.11.2007 ©Turkish Society of Hematology CASE REPORT