LETTERS TO THE EDITOR 49
Table 1 Clinical characteristics of all reports of malignant hypertension with diffuse alveolar haemorrhage.
Case Age Gender Nationality Smoking Previous HT Family history of HT Air travel Ref.
1 34 Male Japanese NR 1 month NR NR 1
2 26 Male North American 1---2 cig./day No Both parents Yes 5
3 26 Male Japanese NR 3 years NR Yes 3
4 38 Male Canadian 9 packs-year 3 months NR NR 4
5 32 Male Japanese NR 5 years Both parents NR 6
6 27 Male Japanese >30 pack-year No NR NR 2
7 51 Male Portuguese >30 pack-year No Mother No ---
HT: systemic hypertension; cig.: cigarette; NR: no reference; Ref.: reference.
However, it is worth noting that no other findings have sup-
ported this hypothesis, and this may be just a non-significant
association. In conclusion, our and previous reports of malig-
nant hypertension associated DAH suggest that high blood
pressure may be a significant cause of alveolar haemorr-
hage. Clinicians caring for DAH patients should be aware of
this association. We also propose large-scale studies on the
association between systemic blood pressure and the risk
of alveolar haemorrhage which could open the way to new
treatment of DAH with BP lowering agent.
Disclosure
The authors report no financial support, off-label or inves-
tigational drug use.
Conflicts of interest
The authors have no conflicts of interest to declare.
References
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2. Park HS, Hong YA, Chung BH, Kim HW, Park CW, Yang CW, et al.
Malignant hypertension with an unusual presentation mimicking
the immune mediated pulmonary renal syndrome. Yonsei Med J.
2012;53:1224---7.
3. Sato Y, Hara S, Yamada K, Fujimoto S. A rare case of alveolar
haemorrhage due to malignant hypertension. Nephrol Dial Trans-
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4. Aithal S, Marley N, Venkat-Raman G. An unusual non-
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5. Dalal P, Phadke G, Gill A, Tarwater K, Misra M, Pele N, et al.
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Joana Clemente Duarte
a,∗
, Rita Leal
b
, Luís Escada
b
,
Tiago M. Alfaro
a
a
Pneumology Unit A, Centro Hospitalar e Universitário de
Coimbra, Coimbra, Portugal
b
Nephrology Unit, Centro Hospitalar e Universitário de
Coimbra, Coimbra, Portugal
∗
Corresponding author.
E-mail address: Joana Duarte 17@hotmail.com
(J.C. Duarte).
http://dx.doi.org/10.1016/j.rppnen.2016.10.002
2173-5115/
© 2016 Sociedade Portuguesa de Pneumologia. Published by Elsevier
Espa˜ na, S.L.U. This is an open access article under the CC BY-NC-ND
license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Mesothelial cyst of the
pulmonary ligament: An
uncommon lesion
Dear Editor,
The importance of a thorough knowledge of thoracic
anatomy is timeless. Lung and pleural anatomy continues to
be a subject for study nowadays, not only due to the greater
spatial resolution of newer diagnostic studies, such as bron-
choscopy, computed tomography and magnetic resonance,
but also because of advances in thoracic surgery.
The pulmonary ligaments are among the lesser known
structures of the thoracic anatomy. The radiological impor-
tance of the pulmonary ligament was first described in
1966 by Rabinowitz and Wolfe,
1
and only very few reports
or series have been found which describe the radiologi-
cal findings of pathologic processes within the pulmonary
ligaments.
1---6
This ligament, just like any other thoracic
anatomical structure can be affected by non-infectious or
infectious inflammatory processes, tumors, congenital or
developmental abnormalities and scarring.
2---6
There are only
a few reports in the literature which mention this anatomical
structure and different pathological process.
The following case description of a cystic lesion within
the right pulmonary ligament illustrates the anatomy and
pathology of this structure:
A 75-year-old woman diagnosed with a pharyngeal can-
cer was referred for magnetic resonance imaging of the
neck and a computed tomography (CT) of the chest and