Assessments were done before (BT) and after (AT) completion of treatment and after the follow up (AF) period with SPSS 2016 and Microsoft Excel 2007. All the chief complaints got statistically highly significant results. Statistically highly significant results were found in visual acuity and PSC type of cataract while Nuclear and cortical type of cataract received sta- tistically significant results. Hence immature cataract can be successfully managed by the selected medicines. PA06 28. AN INVITRO STUDY OF YOGRAJ CHURNA ON ANTIOXIDANT ACTIVITY Shikha Lekharu, Khagen Basumatory. Background: Cellular damage induced by free radicals like reactive oxygen and nitrogen species has been implicated in several disorder and diseases including anemia. Hence naturally occurring antioxidants rich herbs play a vital role in combating these conditions. The present study was carried out to investigate the invitro free radical scavenging capacity of a known Ay- urvedic herbomineral formulation called yograj churna. Methods: Methanol extract of yograj churna were studied for invitro total antioxidant activity. Assays like DPPH, ABTS scavenging to evaluate radical quenching potential were performed. Results: The formulation has shown that IC 50 value for ascorbic acid was 5.6 and for yograj was 15.15 in DPPH. In ABTS, the IC50 value was 237.15 for ascorbic acid and 439.4 for yograj churna. Conclusion: In Indian traditional Ayurvedic system, use of Yograj Churna is in regular practice mainly combating anemia, poisoning, bronchitis, tuberculosis, obstinate skin disease, diabetes, asthma, anorexia etc and many of the rasayana are known for their free radical scavenging activity. Thus the study has validated the potential use of yograj churna as an antioxidant to fight diseases. PAO7 29. A SINGLE CASE STUDY ON VIRAL RETROBULBER OPTIC NEURITIS Nikita Baghel, Prabhakar Vardhan. A 21 year female patient presented with headache, fever, malise and vomiting since 3 days duration and was initial managed as a case of chicken pox. After 6 weeks she developed painless loss of vision in both eye. She admitted in RP Centre Delhi for 7 days, after treatment vision in Right eye was HM and Left eye was 6/36. After 1 week she came to NIA Shalakya opd with C/O blurred vision for treatment. On ocutar examina- tion vision in right eye was CF 2 m and left eye was 6/36 and fundus ex- amination shows hyperaemic disc and no relative afferent pupillary defect. A provisional diagnosis of viral retrobulber optic neuritis (Timir) secondary to demyelination was made as MRI showed demyelinating plaques. Patient was started Saptamrita lauha, Trifala churna, Yograja gugull and Shunthi, Dhanyaka, Mustaka for Amapachana for 15 days and 2 sitting of Marsh nasya with Anutail and Tarpana with Patoladi ghrita for 1 month with in the gap of 7 days. After completion of treatment visual acuity of right eye was improved CF 2 m to 6/18 and 6/36 to 6/24 in left eye without glass and with glass it is 6/9 in both eyes. On follow up MRI at 3 months there was resolution of the demyelinating changes on MRI and the final visual acuity was 6/9P in Right eye and 6/9 in Left eye. This patient needs to be followed up to detect development of demyelinating diseases later in life. PAO8 32. PERSPECTIVES OF TRADITIONAL AND ALLOPATHIC PHYSICIANS ON SPIRITUALITY AND ITS ROLE IN MEDICINE: HISTORICAL TRENDS AND OPPORTUNITY OF CONVERGENCE TOWARDS AN INTEGRATIVE MEDICINE Akhilesh Shukla, Parameshwaran Ramakrishnan. Background: Traditional medicine continued its theory and practice grounded in spirituality/religion while allopathic medicine had alienated itself from spirituality/religion for a while. Allopathic medicine is now re- entering into this realm well equipped with their evidence based tech- niques of enquiry. Objective: We aim to understand the perspectives of AYUSH (Ayur- veda, Yoga, Unani, Siddha and Homeopathy) and allopathic physicians on two key questions. (1) Is spirituality a scientific subject? (2) Is it worthy to be introduced as an academic subject into a health education program? Method: An international pilot study was conducted to collect the data from AYUSH (N ¼ 189) and allopathic professionals (N ¼ 198). Research questionnaires used were (1) Religion and Spirituality in Medicine: Phy- sician's Perspective (RSMPP), and a supplementary questionnaire on Spirituality as a Scientific Subject, (2) Professional Quality of Life and (3) General Health Questionnaire. Result: 84% of AYUSH professionals approved spirituality as a scientific subject and worthy to be introduced in medical school curriculum as compared to 64% of allopathic/modern medical professionals (p<0.005). Conclusion: AYUSH system can contribute significantly in the develop- ment of spirituality as a scientific academic subject but we need to utilize all available scientific tools of modern/evidence based medicine to bring this change. We believe this field of spirituality-medicine could also be the beginning of a truly integrative medicine. PAO9 37. MANAGEMENT OF AICARDI SYNDROME IN AYURVEDA e CASE REPORT Senthiarasi Thamizhmani. Rationale for this case report: Aicardi syndrome is a neurodevelopmental disorder that affects primarily females. It is characterized by three main features e agenesis of corpus callosum, typical chorioretinal lacunae and infantile spasms. It is a very rare disorder. Researches estimate that there are approximately 4000 affected individuals worldwide. The cause is un- known but researchers believe that it is probably the result of a mutation in a gene on the X e chromosome. The outcome of AS is severe, with a high early mortality, considerable morbidity and a generally poor develop- mental outcome. This case report discusses the successful management with Ayurvedic treatment of a case diagnosed as aicardi syndrome. Presenting concerns: 3 years old female child admitted at Govt Ayurveda Medical College Hospital, Nagercoil in 2014 with the complaints of global developmental delay, no eye contact and subnormal intelligence. She is a diagnosed case of Aicardi syndrome. Interventions: Child developed seizure at her age of 5 months which continued till 3 years of age. She was on antiepileptic drugs and hence seizure attack was controlled but she didn't attain the milestones like turning over, sitting, standing, walking, fine motor skills, social and lan- guage development. During this period ayurvedic treatment was started and the child showed good improvement. Outcome: Patient underwent four courses of ayurvedic panchakarma treatment with internal medications and improved well with each course of treatment by attaining the milestones. The child is able to perform her daily activities by herself. Lesson from this case report: this case study shows improvement in attaining developmental milestones with panchakarma procedures in a case diagnosed as Aicardi syndrome. This case study demonstrates the need for further studies to evaluate the outcomes of Ayurvedic in- terventions in developmental disorders of genetic causes. PA10 45. CLINICAL STUDY TO EVALUATE THE EFFICACY OF DRAKSHADI YOGA IN THE MANAGEMENT OF RESPIRATORY ALLERGIC DISORDERS OF CHILDREN Devendra Kumar, Nisha Ojha. Purpose: During recent decades, there has been a dramatic rise in prev- alence of respiratory allergic disease, which include asthma, eczema and allergic rhinitis. Children with Respiratory Allergic Disorders (RAD) expe- rience a lot of problems in their day to day activities. Approximately 40% of children are affected by some form of allergy and respiratory allergies are the most common allergies worldwide. As per different etiological factors and symptoms of respiratory allergic disorders it can be correlated with Abstracts / Journal of Ayurveda and Integrative Medicine 9 (2018) S1eS30 S15