Available online www.jocpr.com Journal of Chemical and Pharmaceutical Research, 2016, 8(5):725-729 Research Article ISSN : 0975-7384 CODEN(USA) : JCPRC5 725 A Novel Clay catalyst: N-Acetylation of Aniline Ismail Shaikh 1 , Sheserao Pawar 1 , Muktar Shaikh 1 and Syed Abed 2 1 P. G. Department of Chemistry, Shri Anand College Pathardi, Dist. Ahmednagar (M.S.) - 414102 2 Goverment College of Arts and Science Aurangabad, Dist. Auranagbad (M.S) _____________________________________________________________________________________________ ABSTRACT N-Acetylation of aniline by using clay as catalyst gives good yield acetic anhydride is commonly used as reagent for acylation of aniline but use of acetic anhydride is banned in Countries due to its utility in narcotics business. In the present investigation, we used acetic acid and novel clay Key words: clay, acetylation, aniline, nanomaterial. _____________________________________________________________________________________________ INTRODUCTION N-acetylation of anilines is a common important chemical reaction in organic synthesis. Various catalyst are reported for N-acetylation which includes heteropolybion based ionic liquids [1]., Acetic anhydride in commonly used as reagent for acetylation of anilines but use of acetic anhydride is banned in some Countries due to its utility in narcotics business thus development new methodology for acetylation of aniline in greener way by using clay. Inspired by the researchers from our City , who [2-8] reported different catalysts for various other organic synthesis, we decided to use clay as a catalyst. Clays have a long history of use as a catalyst in organic synthesis. Clays are easily available and ecofriendly low cost chemical substance. Clays have been used in acid & base catalyzed reaction. Hence in continuation of the work earlier carried, we decided to use clay as catalyst. The clay is characterized by XRD and FESEM. The acylation of anilines and its derivatives has been carried the product is identified from melting point and spectral data. The yield is found to be 80-95%. Preparation of catalyst: This clay is collected from rockey part of Bashir farm At Jatadevale Tq Pathardi Dist Ahmednagar of Maharashtra State India: Crush the clay in fine powder in mortar and pestle wash with distilled water and 0.1 M H 2 SO 4 to remove organic particles soak. This mixture with 24 hour then filters with whatman filter paper. Wash the catalyst with distilled water to remove adsorbed acid. Dry it at 110 0 Cin oven then cool then it is ready to use catalyst in several reactions this catalyst is characterized by using XRD and FESEM technique. Reaction Scheme: NH 2 R H 3 C OH O Clay/Heat on water bath HN CH 3 O R