S-1 Supporting Information Evaluating Single Cell DNA Damage Induced by Enhanced Radiation on Gold Nanofilm Patch Yong Qiao 1,2# , Yuanshuai Zhou 1,4# , Tongqian Xiao 1,4 , Zhiwei Zhang 1 , Liyuan Ma 2,3* , Ming Su 2,3* and Guangli Suo 1* 1 CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Jiangsu, China 215123. 2 Department of Chemical Engineering, Northeastern University, Boston, Massachusetts, United States 02115. 3 Wenzhou Institute of Biomaterials and Engineering, Wenzhou Medical University, Zhejiang, China 325001. 4 University of Chinese Academy of Sciences, Beijing, China 100049. *Corresponding authors. E-mails: glsuo2013@sinano.ac.cn; liy.ma@neu.edu; and m.su@neu.edu. # These authors contributed equally to this work.