1 3
J Anesth
DOI 10.1007/s00540-016-2223-0
ORIGINAL ARTICLE
A nomogram for predicting the need for sciatic nerve block
after total knee arthroplasty
Rovnat Babazade
1,2
· Thilak Sreenivasalu
2,3
· Pankaj Jain
4
· Matthew T. Hutcherson
4
·
Amanda J. Naylor
4
· Jing You
4,5
· Hesham Elsharkawy
4,6
· Ali Sakr Esa Wael
4,6
·
Alparslan Turan
4
Received: 28 December 2015 / Accepted: 20 July 2016
© Japanese Society of Anesthesiologists 2016
nonlinear association between continuous predictors and
SNB was assessed using the restricted cubic spline model.
Results In total 6279 TKA cases involving 2329 patients
with complete datasets were used for building the predic-
tion model, including 276 (12 %) patients who received a
postoperative SNB and 2053 (88 %) patients who did not.
The estimated C statistic of the prediction model was 0.64.
The nomogram is used by first locating the patient position
on each predictor variable scale, which has corresponding
prognostic points. The cut-off of 11.6 % jointly maximizes
the sensitivity and specificity.
Conclusion This is the first study to be published on SNB
prediction after TKA. Our nomogram may prove to be a
useful tool for guiding physicians in terms of their deci-
sions regarding SNB.
Keywords Nomogram · Sciatic nerve block ·
Postoperative pain · Total knee arthroplasty
Introduction
Total knee arthroplasty (TKA) is a commonly performed
procedure in the USA, with the primary aims of relieving
knee pain and improving the quality of life of patients with
end-stage arthritis. An estimated 718,000 procedures were
carried out in 2011 [1, 2], and the demand for primary TKA
is expected to grow in the coming years [3]. TKA causes
severe postoperative pain in 60 % of patients and moderate
pain in 30 % of patients [4]. Therefore, pain management
remains one of the major challenges for anesthesiologists
following TKA.
Postoperative knee pain interferes with physical ther-
apy, mobilization [5], and patient satisfaction, which in
turn results in delayed recovery and higher hospital costs
Abstract
Purpose Sciatic nerve block (SNB) is commonly per-
formed in combination with femoral nerve block (FNB) for
postoperative analgesia following total knee arthroplasty
(TKA). Despite the fact that 10–20 % of TKA patients
require SNB for postoperative posterior knee pain, there
are no existing studies that suggest a model to predict the
need for SNB. The aim of our study was to develop a pre-
diction tool to measure the likelihood of patients undergo-
ing TKA surgery requiring a postoperative SNB.
Methods With institutional review board approval, we
obtained data from the electronic medical record of patients
who underwent TKA at the Cleveland Clinic. A multivari-
able logistic regression was used to estimate the probabil-
ity of requiring a postoperative SNB. Clinicians selected
potential predictors to create a model, and the potential
This report was previously presented, in part, at the American
Society of Anesthesiologists, 2014 Meeting, New Orleans.
* Alparslan Turan
alparslanturan@yahoo.com
http://www.OR.org
1
Department of Anesthesiology, University of Texas Medical
Branch, Galveston, TX, USA
2
Outcomes Research Consortium, Cleveland, OH, USA
3
Department of Anesthesiology, Saint Louis University
Hospital, Saint Louis, MO, USA
4
Department of Outcomes Research, Anesthesiology Institute,
Cleveland Clinic, Cleveland, OH, USA
5
Department of Quantitative Health Sciences, Cleveland
Clinic, Cleveland, OH, USA
6
Anesthesiology, Cleveland Clinic, Lerner College
of Medicine, Cleveland Clinic, Cleveland, OH, USA