Available online at www.ijpsdr.com 105 International Journal of Pharmaceutical Sciences and Drug Research 2017; 9(3): 105-112 Research Article ISSN: 0975-248X CODEN (USA): IJPSPP Formulation and Evaluation of a Moisturizing Cream using Almond Butter M. N. Karemore 1* , Y. M. Charde 1 , P. Dharmadhikari 2 , S. M. Bhise 2 1 Department of Pharmaceutical Sciences, R. T. M. Nagpur University, Nagpur-440033, Maharashtra, India 2 Kamla Nehru Mahavidyalaya Sakkardara Square, Nagpur - 440024, Maharashtra, India Copyright © 2017 M. N. Karemore et al. This is an open access article distributed under the terms of the Creative Commons Attribution- NonCommercial-ShareAlike 4.0 International License which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. ABSTRACT Almond butter is one of the moisturizing agents, which has good emollient and moisturizing properties and hence can be well utilized to design a moisturizing cream, which can provide a good moisturizing property and help to maintain the healthy skin. The aim of the present study is to formulate moisturizing cream using Almond Butter and to evaluate its moisturizing property. In the present study, proper cream base was formulated by taking different trials and evaluated. The cream base showing the best results with respect to pH, thermal stability, total fatty matter and specific gravity was used for the incorporation of the active ingredient in different concentration and was evaluated for physical and chemical parameters. The subjective evaluation of the final product was carried out on volunteers of age 20 - 25 years with dry skin and moisturizing capacity was studied using corneometer. The values for pH, thermal stability, total fatty matter and specific gravity of the selected cream base were found to be within the standard limits. From the results of accelerated stability study of cream, it was found that the cream containing 3% Almond Butter was stable and effective with respect to color, odor, pH, viscosity, globule size and centrifugation. This cream was used for subjective evaluation and it was found that all the candidates experienced desired effect without any irritation. Hence it can be concluded that Almond Butter is having excellent moisturizing effect and can be used as moisturizing agent in different cosmetic products. Keywords: Almond butter, moisturizing agent, Corneometer, subjective evaluation. DOI: 10.25004/IJPSDR.2017.090302 Int. J. Pharm. Sci. Drug Res. 2017; 9(3): 105-112 *Corresponding author: Ms. M. N. Karemore Address: Department of Pharmaceutical Sciences, R. T. M. Nagpur University, Nagpur-440033, Maharashtra, India Tel.: +91-9096039598 E-mail : meghakaremore0687@gmail.com Relevant conflicts of interest/financial disclosures: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Received: 05 April, 2017; Revised: 14 April, 2017; Accepted: 30 April 2017; Published: 29 May 2017 INTRODUCTION The skin is the heaviest single organ of the body, combines with the mucosal lining of the respiratory, digestive, and urogenital tracts to form a capsule which separates the internal body structures from external environment. [1] The skin has several layers. The overlaying outer layer is called epidermis; the layer below epidermis is called dermis. It contains a network