_____________________________________________________________________________________________________ # Third BDS Student, † Reader, ‡ Final BDS Student, *Corresponding author: E-mail: samikshabute50@gamil.com; Journal of Pharmaceutical Research International 33(60B): 3869-3877, 2021; Article no.JPRI.79464 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) Application of Nanoparticles in Endodontics Samiksha Bute a#* , Anuja Ikhar b† , Rushikesh Bhonde b and Rudra Bharate c‡ a Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha, 442001, Maharashtra, India. b Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha, 442001, Maharashtra, India. c Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha. 442001, Maharashtra, India. Authors’ contributions: This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2021/v33i60B35089 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/79464 Received 20 October 2021 Accepted 25 December 2021 Published 28 December 2021 ABSTRACT Nanoscience is a planned blend of nanotechnologies/nanoparticles used in healthcare to discover novel treatment strategies for human infections. N anotechnology is used in many aspects of our daily lives, including medical science. Nanostructures are employed in dental advances, diagnosis and treatment [2]. When compared to traditional materials, Nanoparticles was shown to have significantly superior adhesive plus surface properties. Nanotechnology’s practical implementation in endodontics has allows for new study in this domain. Keywords: Nanoparticles; nanotechnology; endodontics. Review Article