Int. J. Computational Biology and Drug Design, Vol. 9, No. 4, 2016 319 Mathematical modelling of brain bioelectricity: an insightful tutorial Gehan Abouelseoud* and Nour Ismail Faculty of Engineering, Electrical Engineering Department, Alexandria University, Egypt Alexandria 21544, Egypt Email: la.ilah.illa.allah@gmail.com Email: nhassan58@live.com *Corresponding author Amin Shoukry Computer Science and Engineering Department, Egypt Japan University of Science and Technology, P.O. Box 179, New Borg El-Arab City, Alexandria, Egypt Email: amin.shoukry@ejust.edu.eg Jaidaa Mekky Faculty of Medicine, Neuropsychiatry Department, Alexandria University, Egypt Alexandria 21131, Egypt Email: j.mekky@hotmail.co.uk Abstract: Mathematical modelling of brain bioelectricity is important for different applications ranging from medicine to engineering sciences. This tutorial aims to offer a global view of available modelling approaches and their suitability for different applications. It is written in a way that is intended to equally help engineers (with low biology background) and medical practitioners (with low mathematical background) in getting a quick grasp of the subject. Although, the tutorial focuses on brain bioelectricity, reading it can give insight into basic concepts which are essential for the mathematical modelling of any biological process in general. Keywords: neuron compartmental models; Poisson’s equation; effective medium; FEM; finite element method; volume conductor; mathematical modelling of biological processes. Copyright © 2016 Inderscience Enterprises Ltd.