Compression Orthosis as Factor that Reduces Complications in Conservative Breast Cancer Surgery with Respect to the Use of a Compressive Dressing Jose Manuel de León Carrillo *1 , Carmen Delgado Jiménez 2 , Carmen Victoria Almeida González 2 , Gonzalo de Castro Parga 3 , Inmaculada Alonso Vargas 4 , Pilar Rioja Torres 5 , Maria José Cantero Rodríguez 2 , Carmen Gata Cala 1 , María Ermitas Dávila Casal 3 , Maria Jesús Sánchez Sánchez 4 , Rafael Galisteo Domínguez 2 , Alda Cardesin Revilla 6 , Antonio Piñero Madrona 7 1. Hospital Universitario Virgen del Rocío, Sevilla, España 2. Hospital Universitario Virgen de Valme, Sevilla, España 3. Complejo Hospitalario Universitario de Vigo, Vigo, Pontevedra, España 4. Hospital Clínic, Barcelona, España 5. Hospital Universitario Reina Sofía, Córdoba, España 6. Hospital Parc Taulí, Sabadell, Barcelona, España 7. Director Grupo Estudios Senológicos de la SESPM Br J Cancer Res 2018,1:3 178 British Journal of Cancer Research 2018; 1(3): 178 - 185 . doi: 10.31488/bjcr.114 Research Article British Journal of Cancer Research * Corresponding author: Jose Manuel de León Carrillo, Hospital Universitario Virgen del Rocío, Sevilla, España, Spain, E-mail: pepedleon@telefonica.net Received: July 27, 2018; Accepted: August 11, 2018; Published: August 14 , 2018 Abstract Objectives: To demonstrate that the use of controlled compression orthosis versus classic compressive dressing reduces postoperative complications in conservative breast cancer surgery. Patients and Method: The 186 patients who were randomised to use an orthosis or a compressive dressing after conservative breast cancer surgery were included. Clinical-pathological variables were recorded and their relationship with the development of postoperative complications in the two weeks following surgery was studied, and a multivariate analysis was carried out with significant variables or with a tendency towards such a relationship. Results: As variables related to the appearance of postoperative complications in the two weeks following surgery we measured: medium or large size (P=.023), the use of a compressive dressing vs. an orthosis (P =.009), the intrinsic Her2neu subtype (P =.004), the use of breast drainage (P =.010) or axillary drainage (P =.017) and the extensive lymphadenectomy (P=.010). The use of a compressive dressing, the intrinsic Her2neu subtype and the use of breast drain- age, persist as independent factors after the multivariate analysis. Conclusion: The compression ortho- sis versus the compressive dressing is an independent protective factor for early postoperative compli- cations in breast cancer. Conservative breast and axillary surgery is the reference standard [1-6] in the surgical treatment of breast cancer, in line with the principle of applying the minimum effective treatment at both the breast and axillary levels. The evolu- tion and surge in oncoplastic breast surgery [7] and selec- tive sentinel lymph node biopsy for ganglionic staging8 currently include both surgical procedures in 80% and 95% of the surgical procedures indicated to achieve the Introduction Keywords: breast cancer; breast-conserving therapy; postoperative complications; occlusive bandage; compressive garment