2114 Indian Journal of Forensic Medicine & Toxicology, April-June 2021, Vol. 15, No. 2 The Indonesian Version of SF-36 Questionnaire: Validity and Reliability Testing in Indonesian Healthcare Workers Who Handle Infectious Diseases Berliana Devianti Putri 1 , Nur Septia Handayani 1 , Sahra Zafhira Ekayafta 2 , Ajeng Dilla Lestari 2 1 Lecturer, 2 Student, Faculty of Vocational Studies, Universitas Airlangga, Surabaya, Indonesia Abstract Quality of life is a parameter to measure the position of life for high-risk people, including healthcare workers who handle infectious disease. Quality of life affects productivity and performance. A lot of instruments can be used to measure the quality of life, which one is the 36-item Short From Health Survey (SF-36). It is an international standard questionnaire which measuring health-related quality of life, so a translation process into Indonesian is necessary. The aim of this study is to evaluate the validity and reliability of SF-36 questionnare on Indonesian version. This study was an observational analytic with a cross-sectional design. This study divided into 2 stages, ie. translating questionnaire into Indonesian version, then testing it with respondents. We evaluated 45 healthcare workers working in the COVID-19 isolation room. Data were taken from September to October 2020. This study was analyzed by Pearson Correlation and Cronbach’ alpha with α=5% and using SPSS v.23 software. Results showed that the overall cronbach’ alpha coeffcient was 0.883, while the fve dimensions were >0.70 (physical function, vitality, mental health, bodily pain, and general health). But, the role physical, role emotional, and social function dimensions had cronbach’ alpha coeffcient 0.6-0.7. The Indonesian version of SF-36 was valid and reliable, so it could be used as a instruments for measuring health related quality of life among healthcare workers who handle infectious diseases, especially in COVID-19. Keywords : Health related quality of life, 36-Item Short From Health Survey (SF-36), Healthcare workers, Validity, Reliability Corresponding Author: Berliana Devianti Putri Email: berliana.devianti@vokasi.unair.ac.id Background Quality of Life (QoL) is a multidimensional construct infuenced by aspects of work and personal life, physical and phsychological health, social relationships, and environment in which a person lives. QoL has long been recognized as a measure in high-risk populations, including workers, because work is a social activity that can impact health 1,2 . Health-Related Quality of Life (HRQL) is a part of QoL which measure individual health status. It can capture individual’s subjective evaluations of their current health status, and comparing it in last year 3 . The health related quality of life in high-risk group has been the subject of extensive investigation, especially in patients with peacemaker, cancer, and others who are in emergency department. But study focussing on the health related quality of life in healthcare worker is rare and it need to be better appreciated, especially in healthcare workers who handle infectious diseases 3-5 . The quality of life aspects could be help to reduce negative effects on their lives. The 36-item Short From Health Survey (SF-36) has been well-known as an international standard questionnaire which measuring health-related quality of life. It involves 8 domains from physical and mental aspects: physical function, vitality, mental health, bodily pain, role physical, role emotional, social function, and general health 6 . There is no appropriate Indonesian version of SF-36 for healthcare workers