Kar A et al JMSCR Volume 05 Issue 11 November 2017 Page 30075 JMSCR Vol||05||Issue||11||Page 30075-30079||November 2017 Spirometric Assessment of Pulmonary Function in Non Smoker Patients of Coronary Artery Disease and/or Hypertension and Comparison with Healthy Subjects Authors Adrita Kar, Biswajit Majumder, Atin Dey R G Kar Medical College, Kolkata Corresponding Author Biswajit Majumder Address-181B/1Kabi Guru Sarani, Kolkata Email: majumderbiswajit1972@gmail.com Abstract Coronary artery disease and hypertension are major health problems in today’s world. Recently lot of interest has been generated regarding the possible systemic and pulmonary effects of the pervasive low grade inflammation that is present in coronary artery disease and hypertension. Many studies have objectively demonstrated undisputable evidence of airflow limitation in a setting of CAD and hypertension accompanied by a low FEV1, FVC and FEV1/FVC ratio. In our study, we compared the spirometric indices of 100 patients of CAD and/or hypertension to healthy subjects. It was found that 25% of such patients suffered from undiagnosed airflow limitation as compared to only 2% in healthy patients. The difference was significant. Therefore we recommend that spirometric screening is an easy, non invasive and inexpensive tool to diagnose undetected obstructive airway disesase in such patients and treat the same. Introduction Coronary artery disease (CAD) refers to the narrowing of the coronary arterial lumen, mainly arising as a complication of the atherosclerotic process. In the year 2004, CAD has claimed 7.2 million lives worldwide and accounted for the loss of an astounding 63 million disability adjusted life years (DALY). Each year there are about 5.8 million new cases of coronary artery disease and presently more than 40 million people suffer from various forms of coronary artery disease and its sequelae (1) . In India alone, in the year 2004, there has been 1.46 million deaths due to coronary artery disease, that is almost 130.1 deaths per lakh population and about 207.7 age adjusted deaths per lakh population. It has caused a loss of 1,931 age adjusted DALYs per lakh population. (2) According to the popular textbook and JNC 7 criteria, a person is said to have hypertension if his seated systolic blood pressure is more than 140 mm Hg and diastolic blood pressure is more than 90 mm Hg on at least two or more separate outpatient visits (3,4) . In India hypertension has caused loss of 9.4 million lives and 7% of DALYs in the year 2010. This silent killer is on the rise in most low and middle income countries and India is no exception. It is estimated that 16% of ischaemic heart diseases, 21% of peripheral vascular disease, 24% acute myocardial infarction and 29 % of strokes are directly or indirectly attributable to hypertensive etiologies in our country. (5) It has been seen that these diseases affect the spirometric indices of a patient even in the www.jmscr.igmpublication.org Impact Factor 5.84 Index Copernicus Value: 71.58 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: https://dx.doi.org/10.18535/jmscr/v5i11.42