_____________________________________________________________________________________________________ *Corresponding author: E-mail: jenningshernandez7@gmail.com; International Neuropsychiatric Disease Journal 18(1): 43-47, 2022; Article no.INDJ.91853 ISSN: 2321-7235, NLM ID: 101632319 The Mental Health Syndrome Known as Alice in Wonderland - A Case Report Jennings Hernandez a* a Washington University of Health and Science, United States of America. Author’s contribution The sole author designed, analysed, interpreted and prepared the manuscript. Article Information DOI: 10.9734/INDJ/2022/v18i1344 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/91853 Received 11 July 2022 Accepted 15 September 2022 Published 17 September 2022 ABSTRACT The Alice in Wonderland Syndrome (AIWS) is a rare neurological and psychiatric condition, represented as the appearance of disorienting perceptual disorder with occasional episodes of bizarre visual illusions and spatial distortions. It was first introduced by John Todd in 1955, based on the literary chronicles of the strange encounters described by Lewis Carroll in Alice in Wonderland books. A 30-year-old healthy male presented to the doctor’s office with left -sided headaches lasting 24 hours and preceded by an aura. During these auras, the patient was experiencing erratic behaviors consistent with the phenomena experienced by Alice, the main character in the world-famous story. He reported objects being larger and further away than they really were and his hands appearing smaller than they really were. Symptoms lasted up to 45 minutes. All clinical and diagnostic workups and evaluations were unremarkable, and the patient was treated for migraines with auras using Valproic Acid. During his follow-up at 3 months intervals, the patient continued with symptoms, and his medication dosage was increased. In his next follow- up three months later, he described having no more symptoms. AIWS has been found to be related to migraines with preceding auras. It is both common in pediatrics as well as in adults. I present an AIWS case co-existent with aura migraines. Keywords: Alice in wonderland syndrome; metamorphopsias; Todd’s Syndrome; lilliputian hallucinations; macropsia; micropsia; teleopsia; pelopsia; aschematia; dysmetropsia; migraines; aura. Case Study